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image: Culturing Changes Cells

Culturing Changes Cells

By | February 3, 2015

Within days of their transfer to a dish, a certain epigenetic mark vanishes from mouse cells.

2 Comments

image: Benefits of Missing MYC

Benefits of Missing MYC

By | January 22, 2015

Mice engineered to have just one copy of the gene Myc live longer, healthier lives than wild-type animals.

1 Comment

image: Stem Cell Divisions Help Explain Cancer Risk

Stem Cell Divisions Help Explain Cancer Risk

By | January 1, 2015

An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk—more so than heritable mutations and environmental factors combined.  

7 Comments

image: Focus on Sex

Focus on Sex

By | December 29, 2014

In 2014, new research findings and guidelines brought increased attention to biological differences between males and females.

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image: Vanishing Y Chromosomes

Vanishing Y Chromosomes

By | December 4, 2014

A new study reveals an association between smoking and rates of Y chromosome loss in blood cells, which may explain elevated cancer risk among male smokers.

1 Comment

image: Illuminating the Interactome

Illuminating the Interactome

By | November 20, 2014

A massive screen yields the most comprehensive map of binary human protein interactions to date.

10 Comments

image: Genome Digest

Genome Digest

By | July 28, 2014

What researchers are learning as they sequence, map, and decode species’ genomes

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image: Epigenetic Changes Can Cause Cancer

Epigenetic Changes Can Cause Cancer

By | July 25, 2014

A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model. 

4 Comments

image: A Multi-Cancer Diagnostic?

A Multi-Cancer Diagnostic?

By | July 14, 2014

Researchers report an ability to detect several types of cancer in blood samples based on signatures of immune response, but some are skeptical about the utility of such a test.

3 Comments

image: Targeted Brain Cancer Vaccine

Targeted Brain Cancer Vaccine

By | June 25, 2014

Mouse study demonstrates the ability of a cancer vaccine targeted against a specific oncogenic mutation to elicit a protective anti-tumor immune response. 

1 Comment

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