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image: Broad Wins CRISPR Patent Interference Case

Broad Wins CRISPR Patent Interference Case

By | February 15, 2017

The USPTO’s Patent Trial and Appeal Board has ruled in favor of the Broad Institute of MIT and Harvard retaining intellectual property rights covered by its patents for CRISPR gene-editing technology.

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image: Toward Killing Cancer with Bacteria

Toward Killing Cancer with Bacteria

By | February 8, 2017

Researchers employ an engineered microbe to destroy tumor cells in mice.

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image: Non-Chromosomal DNA Drives Tumor Evolution

Non-Chromosomal DNA Drives Tumor Evolution

By | February 8, 2017

Researchers discover that short pieces of DNA harboring oncogenes are relatively widespread in cancer.

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image: Lipids Take the Lead in Metastasis

Lipids Take the Lead in Metastasis

By | January 20, 2017

Researchers find diverse ways that the molecules can regulate cancer’s spread.

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A cell phone–based microscope can identify mutations in tumor tissue and image products of DNA sequencing reactions.

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image: Speaking of Science: 2016

Speaking of Science: 2016

By | December 19, 2016

Selected quotes from an eventful year

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image: Top Technical Advances 2016

Top Technical Advances 2016

By | December 15, 2016

The year’s most impressive achievements include methods to watch translation in cells, trace cell fates, avoid mitochondrial mutations, edit DNA, and build antibiotics from scratch.

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A noninvasive microscopy technique that exploits NADH fluorescence enables researchers to observe how mitochondria alter their shape and arrangement in human tissue.

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image: Smoking-Linked Cancer Mutations Mapped

Smoking-Linked Cancer Mutations Mapped

By | November 3, 2016

Scientists produce a detailed genomic map of mutations and epigenetic changes associated with smoking tobacco across 17 tumor types. 

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image: Nixing NETs to Prevent Metastasis

Nixing NETs to Prevent Metastasis

By | October 19, 2016

Researchers discover that neutrophil extracellular traps help cancers spread, and design enzyme-loaded nanoparticles to destroy them.

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