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image: Top Technical Advances 2015

Top Technical Advances 2015

By | December 24, 2015

The Scientist’s choice of major improvements in imaging, optogenetics, single-cell analyses, and CRISPR

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image: Year in Review: CRISPR Blossoms

Year in Review: CRISPR Blossoms

By | December 16, 2015

As researchers work to improve the precision gene-editing technology, the community discusses the best way to use it.

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image: Microbes Play Role in Anti-Tumor Response

Microbes Play Role in Anti-Tumor Response

By | November 5, 2015

Gut microbiome composition can influence the effectiveness of cancer immunotherapy in mice.

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image: Imaging Live Tissue Without Fluorescence

Imaging Live Tissue Without Fluorescence

By | October 30, 2015

Modifying a vibration-based optical technique can capture images of living tissues, researchers show. 

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image: Double-Edged Enzyme

Double-Edged Enzyme

By | August 13, 2015

Researchers find evidence to suggest why an enzyme crucial for fighting off malaria infection is linked to a form of lymphoma.

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image: Toward Blood-based Cancer Detection

Toward Blood-based Cancer Detection

By | July 7, 2015

Circulating tumor cells, exosomes, and DNA can improve the diagnosis of many cancers. But are liquid biopsies ready for prime time?

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image: Neanderthal-Human Hybrid Unearthed

Neanderthal-Human Hybrid Unearthed

By | June 22, 2015

DNA from the 40,000-year-old bones of a modern human found in Europe contains Neanderthal genes.

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image: Cancer-Driving Mutations Common in Normal Skin Cells

Cancer-Driving Mutations Common in Normal Skin Cells

By | May 21, 2015

A deep-sequencing analysis reveals that non-malignant skin cells harbor many more cancer-driving mutations than previously expected. 

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image: Personalized Devices Predict Cancer Drug Response

Personalized Devices Predict Cancer Drug Response

By | April 22, 2015

Two teams have developed tumor-implantable drug delivery devices to study real-time responses to multiple therapies in cancer patients.

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image: Cancer Sequencing Controls

Cancer Sequencing Controls

By | April 15, 2015

Comparing a patient’s tumor DNA sequence with that of her normal tissue can improve researchers’ identification of disease-associated mutations.

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