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image: Insulin Interference Triggers Cancer-Linked Cachexia

Insulin Interference Triggers Cancer-Linked Cachexia

By | April 6, 2015

A tumor-secreted protein interferes with insulin signaling to cause cancer-linked muscle wasting in fruit flies. 


image: Personalized Cancer Vaccines

Personalized Cancer Vaccines

By | April 2, 2015

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 


image: Opinion: Upgrading Cancer Prevention

Opinion: Upgrading Cancer Prevention

By | April 1, 2015

Preemptive detection and intervention will be key to easing the growing burden of cancer, particularly in developing countries.

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image: Opinion: Making Cancer Vaccines Work

Opinion: Making Cancer Vaccines Work

By | March 31, 2015

Armed with the right adjuvant system, vaccines are poised to tackle one of the world’s most intractable diseases. 


image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.


image: T Cells of the Skin

T Cells of the Skin

By | March 18, 2015

A census of adaptive immune system components in human skin reveals a variety of resident and traveling memory T cells.


image: Engineered Biomarkers Could ID Cancer Cells

Engineered Biomarkers Could ID Cancer Cells

By | February 23, 2015

Scientists develop synthetic blood-based biomarkers to amplify tumor signals in a mouse model.


image: The Dark Side of Melanin

The Dark Side of Melanin

By | February 19, 2015

Researchers uncover a previously unknown way UV light can act on melanin, spurring cancer-causing mutations hours after sun exposure.


image: Exploring the Epigenome

Exploring the Epigenome

By | February 18, 2015

A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks.


image: Long-Lived Immunotherapy Stem Cells

Long-Lived Immunotherapy Stem Cells

By | February 4, 2015

Genetically modified T memory stem cells persist in patients for more than 10 years, and can differentiate into a variety of T cell types.

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