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image: Genome Digest

Genome Digest

By | July 28, 2014

What researchers are learning as they sequence, map, and decode species’ genomes

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image: Epigenetic Changes Can Cause Cancer

Epigenetic Changes Can Cause Cancer

By | July 25, 2014

A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model. 

4 Comments

image: A Multi-Cancer Diagnostic?

A Multi-Cancer Diagnostic?

By | July 14, 2014

Researchers report an ability to detect several types of cancer in blood samples based on signatures of immune response, but some are skeptical about the utility of such a test.

3 Comments

image: Targeted Brain Cancer Vaccine

Targeted Brain Cancer Vaccine

By | June 25, 2014

Mouse study demonstrates the ability of a cancer vaccine targeted against a specific oncogenic mutation to elicit a protective anti-tumor immune response. 

1 Comment

Scientists generate tumor-targeting molecules that can be used for imaging and treatment.

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image: Genome Digest

Genome Digest

By | June 11, 2014

What researchers are learning as they sequence, map, and decode species’ genomes

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image: Making Sense of the Tumor Exome

Making Sense of the Tumor Exome

By | May 18, 2014

An algorithm can pick out biologically and clinically meaningful variants from whole-exome sequences of tumors.

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image: Opinion: Overcoming Cancer’s Complexities

Opinion: Overcoming Cancer’s Complexities

By , , and | April 11, 2014

Considering “targeted therapeutics” in the face of intra-patient heterogeneity. 

2 Comments

image: Obesity Complicates Colorectal Cancer

Obesity Complicates Colorectal Cancer

By | April 9, 2014

Study finds that prediagnosis obesity is predictive of poor prognosis, even among patients who have a molecular marker associated with better disease outcome.

1 Comment

image: Epigenetic Cancer Therapy Clears Phase I

Epigenetic Cancer Therapy Clears Phase I

By | April 7, 2014

Investigational drug that inhibits proteins involved with epigenetic regulation shows activity against certain blood cancers in an early-stage clinical trial.

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