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image: Toward Blood-based Cancer Detection

Toward Blood-based Cancer Detection

By | July 7, 2015

Circulating tumor cells, exosomes, and DNA can improve the diagnosis of many cancers. But are liquid biopsies ready for prime time?

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image: Cancer-Driving Mutations Common in Normal Skin Cells

Cancer-Driving Mutations Common in Normal Skin Cells

By | May 21, 2015

A deep-sequencing analysis reveals that non-malignant skin cells harbor many more cancer-driving mutations than previously expected. 

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While some in the scientific and religious communities have declared an end to the tensions between faith and fact, the conflict continues to have impacts on health, politics, and the environment.

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image: Personalized Devices Predict Cancer Drug Response

Personalized Devices Predict Cancer Drug Response

By | April 22, 2015

Two teams have developed tumor-implantable drug delivery devices to study real-time responses to multiple therapies in cancer patients.

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image: Cancer Sequencing Controls

Cancer Sequencing Controls

By | April 15, 2015

Comparing a patient’s tumor DNA sequence with that of her normal tissue can improve researchers’ identification of disease-associated mutations.

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image: Clam Cancer Rips Along Atlantic Coast

Clam Cancer Rips Along Atlantic Coast

By | April 9, 2015

A leukemia that’s killing far-flung populations of softshell clams may be contagious. 

2 Comments

image: Insulin Interference Triggers Cancer-Linked Cachexia

Insulin Interference Triggers Cancer-Linked Cachexia

By | April 6, 2015

A tumor-secreted protein interferes with insulin signaling to cause cancer-linked muscle wasting in fruit flies. 

2 Comments

image: Personalized Cancer Vaccines

Personalized Cancer Vaccines

By | April 2, 2015

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 

2 Comments

image: Opinion: Upgrading Cancer Prevention

Opinion: Upgrading Cancer Prevention

By | April 1, 2015

Preemptive detection and intervention will be key to easing the growing burden of cancer, particularly in developing countries.

1 Comment

image: Opinion: Making Cancer Vaccines Work

Opinion: Making Cancer Vaccines Work

By | March 31, 2015

Armed with the right adjuvant system, vaccines are poised to tackle one of the world’s most intractable diseases. 

4 Comments

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    The European Patent Office will grant patent rights over the use of CRISPR in all cell types to a University of California team, contrasting with a recent decision in the U.S.

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    With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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    The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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