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image: How Statistics Weakened mRNA’s Predictive Power

How Statistics Weakened mRNA’s Predictive Power

By | May 22, 2017

Transcript abundance isn’t a reliable indicator of protein quantity, contrary to studies’ suggestions. 

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image: The RNA Age: A Primer

The RNA Age: A Primer

By | May 11, 2017

Our guide to all known forms of RNA, from cis-NAT to vault RNA and everything in between.

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image: Genome Digest

Genome Digest

By | May 11, 2017

What researchers are learning as they sequence, map, and decode species’ genomes

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image: Opinion: Get to Know Why People Openly Share Genomic Data

Opinion: Get to Know Why People Openly Share Genomic Data

By | May 9, 2017

It’s not only about health but also about exploring ancestry and contributing to science.

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By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease

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image: CRISPR Corrects Duchenne-Causing Mutations

CRISPR Corrects Duchenne-Causing Mutations

By | April 12, 2017

Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.

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Octopus, cuttlefish, and squid extensively edit messenger RNAs in an evolutionarily conserved process. 

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image: Cross-Sample Sequencing Contamination Galore

Cross-Sample Sequencing Contamination Galore

By | April 5, 2017

Scientists conducting a large-scale, comparative transcriptomics project have inadvertently highlighted widespread contamination in sequencing data.

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image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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