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image: Dengue Infection Impairs Immune Defense Against Zika

Dengue Infection Impairs Immune Defense Against Zika

By | August 18, 2017

A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.

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image: Vitamin C Blocks Leukemia Progression in Mice

Vitamin C Blocks Leukemia Progression in Mice

By | August 17, 2017

High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.

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There is little evidence that full treatment durations discourage the development of drug-resistant bacteria.

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image: The Cancer Genes Needed for Immunotherapy Response

The Cancer Genes Needed for Immunotherapy Response

By | August 7, 2017

Using a large CRISPR-based screen, researchers find possible genetic culprits for patients not having success with immune checkpoint inhibitors.  

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Two freely available databases include data on hundreds of human cancer cell lines. 

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image: Stem Cells Seek Out Tumors Based on Stiffness

Stem Cells Seek Out Tumors Based on Stiffness

By | July 26, 2017

The technique, demonstrated in mice using engineered mesenchymal stem cells, has potential for both diagnosis and treatment.

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image: Anti-Preeclampsia Hormone Discovered

Anti-Preeclampsia Hormone Discovered

By | June 29, 2017

A small, placenta-produced peptide fixes the pregnancy-related condition in mice. 

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image: Transgenic Mouse Illuminates Melanoma Metastasis

Transgenic Mouse Illuminates Melanoma Metastasis

By | June 28, 2017

Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels. 

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An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.

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A study suggests that “chief” cells in the stomach act as reserve stem cells that are activated by tissue damage and may be the long-sought source of gastric cancer.

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