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image: Abundant Sequence Errors in Public Databases

Abundant Sequence Errors in Public Databases

By | February 16, 2017

A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.

2 Comments

image: Broad Wins CRISPR Patent Interference Case

Broad Wins CRISPR Patent Interference Case

By | February 15, 2017

The USPTO’s Patent Trial and Appeal Board has ruled in favor of the Broad Institute of MIT and Harvard retaining intellectual property rights covered by its patents for CRISPR gene-editing technology.

6 Comments

image: Pardis Sabeti: An American Scientist Born in Iran

Pardis Sabeti: An American Scientist Born in Iran

By | February 9, 2017

When she entered the U.S. shortly before the Iranian revolution of 1979, the now 41-year-old geneticist was a refugee toddler. 

5 Comments

image: Toward Killing Cancer with Bacteria

Toward Killing Cancer with Bacteria

By | February 8, 2017

Researchers employ an engineered microbe to destroy tumor cells in mice.

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image: Non-Chromosomal DNA Drives Tumor Evolution

Non-Chromosomal DNA Drives Tumor Evolution

By | February 8, 2017

Researchers discover that short pieces of DNA harboring oncogenes are relatively widespread in cancer.

1 Comment

image: Improved Semisynthetic Organism Created

Improved Semisynthetic Organism Created

By | January 23, 2017

Researchers generate an organism that can replicate artificial base pairs indefinitely.

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image: Lipids Take the Lead in Metastasis

Lipids Take the Lead in Metastasis

By | January 20, 2017

Researchers find diverse ways that the molecules can regulate cancer’s spread.

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A cell phone–based microscope can identify mutations in tumor tissue and image products of DNA sequencing reactions.

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image: As the Brain Ages, Glial-Cell Gene Expression Changes Most

As the Brain Ages, Glial-Cell Gene Expression Changes Most

By | January 10, 2017

Researchers describe how gene expression in different human brain regions is altered with age.

1 Comment

image: Exome Study Reveals Novel Disease-Linked Alleles

Exome Study Reveals Novel Disease-Linked Alleles

By | December 22, 2016

By combining whole-exome sequencing data with longitudinal electronic health record information for 50,000 individuals, researchers have identified novel disease associations.

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