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Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock
Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock
Cells found in different branches of a tree have different patterns of DNA methylation, changes in which accumulate over time.
Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock
Long-Lived Trees’ Epigenetic Mutations Serve as a Molecular Clock

Cells found in different branches of a tree have different patterns of DNA methylation, changes in which accumulate over time.

Cells found in different branches of a tree have different patterns of DNA methylation, changes in which accumulate over time.

DNA methylation, genetics & genomics

Genetic Reprogramming Restores Vision in Mice: Study
Max Kozlov | Dec 6, 2020 | 5 min read
Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.
agouti mice Epigenetic Inheritance the scientist
Classic Mechanism of Epigenetic Inheritance Is Rare, Not the Rule
Ashley Yeager | Mar 1, 2019 | 3 min read
A study suggests that the direct transfer of DNA methylation marks from one generation to the next is much less common than scientists previously thought.
Exome Sequencing Helps Crack Rare Disease Diagnosis
Amanda B. Keener | May 1, 2018 | 10+ min read
Clinical analyses of patients’ gene sequences are helping to provide answers where none were available before.
New Techniques Detail Embryos’ First Hours and Days
Jef Akst | Dec 1, 2017 | 10+ min read
New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.
Infographic: How Embryos Take Control of Their Own Development
Jef Akst | Nov 30, 2017 | 3 min read
The switch from maternal factors involves dynamic reprogramming of the zygotic genome.
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017 | 10+ min read
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
Infographic: The Various Forms of Methylated DNA
Skirmantas Kriaucionis | Aug 31, 2017 | 1 min read
To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.
Methylation Maestro
Anna Azvolinsky | Jan 1, 2017 | 9 min read
After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.
Transgenerational Epigenetics Prepares Plants for Drought
Ben Andrew Henry | Jan 1, 2017 | 2 min read
Plants grown in dry soil produce offspring that are hardier in drought conditions, and DNA methylation appears responsible. 
Characterizing the Imprintome
Amber Dance | Jan 1, 2017 | 8 min read
Three techniques for identifying the collection of maternal and paternal genes silenced in offspring
New Epigenetic Mark Confirmed in Mammals
Jef Akst | Apr 1, 2016 | 2 min read
Methylation on adenine bases is involved in the dampening of gene expression in mammalian cells, according to a study.
Managing Methylation
Karen Zusi | Jan 1, 2016 | 2 min read
A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.
Messages in the Noise
Sarah C.P. Williams | Aug 1, 2015 | 7 min read
After spending more than a decade developing tools to study patterns in gene sequences, bioinformaticians are now working on programs to analyze epigenomics data.
Leaving an Imprint
Anna Azvolinsky | Aug 1, 2015 | 8 min read
Among the first to discover epigenetic reprogramming during mammalian development, Wolf Reik has been studying the dynamics of the epigenome for 30 years.
Methylation Predicts Mortality
Kerry Grens | Feb 3, 2015 | 1 min read
A study finds a link between patterns of methylation in the human genome and people’s life span.
Clocking Epigenetics
Abby Olena, PhD | Oct 22, 2013 | 2 min read
DNA methylation status can predict age in various human tissues, a study shows.
The Epigenetic Lnc
Kevin V. Morris | Oct 1, 2012 | 1 min read
Long non-protein-coding RNA (lncRNA) sequences are often transcribed from the opposite, or antisense, strand of a protein coding gene. In the past few years, research has shown that these lncRNAs play a number of regulatory roles in the cell. For exa
Lamarck and the Missing Lnc
Kevin V. Morris | Oct 1, 2012 | 8 min read
Epigenetic changes accrued over an organism’s lifetime may leave a permanent heritable mark on the genome, through the help of long noncoding RNAs.
Combing the Cancer Genome
Carina Storrs | Mar 1, 2012 | 8 min read
A guided tour through the main online resources for analyzing cancer genomics data
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