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bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Engineering the Microbiome: CRISPR Leads the Way
Engineering the Microbiome: CRISPR Leads the Way

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Magazine Issue

Image showing monoclonal antibody treatment
The Resilience of Monoclonal Antibodies and their Makers
Laura Tran, PhD | Mar 15, 2024 | 10+ min read
The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.
TK
Bat Immune Systems: The Original Antivirus Programs
Hannah Thomasy, PhD | Mar 15, 2024 | 3 min read
Bats stay healthy while hosting some of the world’s deadliest viruses. Scientists are just beginning to understand how.
TK
Infographic: Vaccinating Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 1 min read
Cancer vaccines offer the opportunity to use the patient’s own immune system in the fight against tumors.
TK
Infographic: Understanding CAR-T vs TCR Approaches
Danielle Gerhard, PhD | Mar 15, 2024 | 3 min read
Living drugs get a boost from emerging engineering strategies that focus on safety and specificity.
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Infographic: Engineering Microbiomes with CRISPR
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 2 min read
Researchers are using CRISPR for precise genetic manipulation of human-associated microbes as a promising avenue for improving human health.
3D Rendering of Molecular Interaction in CAR Chimeric Antigen Receptor
Next-generation CAR and TCR Cancer Therapies
Danielle Gerhard, PhD | Mar 15, 2024 | 10+ min read
From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
danielle gerhard
Meet the Team: Danielle Gerhard, PhD
Danielle Gerhard, PhD | Mar 15, 2024 | 3 min read
After years in the lab, Danielle Gerhard put down the pipette and picked up the pen to follow her passion for storytelling.
Robot hand holding glass sphere with glowing fiber neon communication wires
Gazing into Science’s Crystal Ball
Meenakshi Prabhune, PhD | Mar 15, 2024 | 3 min read
Basic research successes offer glimpses into future scientific advancements, but the outcomes are subject to change.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
Illustration showing mouse being injected with AAV mixture
Infographic: Taking AAV screening to the next level
Mariella Bodemeier Loayza Careaga, PhD | Mar 8, 2024 | 2 min read
DNA barcodes in AAV vectors technology simplified AAV screening.
Women scientists work in a laboratory with a microscope and test tubes.
From Stepping Aside to Stepping Forward
Meenakshi Prabhune, PhD | Mar 1, 2024 | 2 min read
Women in science have come a long way, and they do not intend to stop.
3D rendered single cell next to a cluster of cells, illustrating the concept of stem cell differentiation and proliferation.
Selecting Cytokines for Organoid Cultures
The Scientist Staff | Mar 1, 2024 | 2 min read
Scientists optimize organoid culture growth and consistency with validated growth factor panels.
<style type="text/css" >p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 13.8px Helvetica; color: #000000}</style>Purple cartoon of candida auris with lines pointing places the bacteria clings to in a hospital, like a wheelchair, bed, skin, and catheter.&nbsp;
Seeking Solutions for a Sticky Situation
Danielle Gerhard, PhD | Mar 1, 2024 | 2 min read
To cling to everything from catheters to skin, Candida auris uses a unique approach.
A researcher looks at the screen of an imaging equipment. She sees a picture of a Western blot membrane.
The Mysterious Western Blot Message
Mariella Bodemeier Loayza Careaga, PhD | Mar 1, 2024 | 2 min read
Elissavet Chartampila meticulously crafted handwritten labels for her lab tools. Little did she know that some labels last forever.
March Digest crossword image
Science Crossword Puzzle
Stella Zawistowski | Mar 1, 2024 | 1 min read
Put on your thinking cap, and take on this fun challenge.
Fluorescent microscopy image of an embryo model representing four tissue layers of this developmental stage. Cyan-labeled cells are clustered at the top of an ovoid structure, underneath them are yellow-labeled cells and under them red-labeled cells, and surrounding all three layers are white labeled cells.
The First Human Embryo Model From Embryonic Stem Cells
Shelby Bradford, PhD | Mar 1, 2024 | 2 min read
Jacob Hanna developed a method for replicating embryogenesis outside of the uterus to understand the underlying mechanisms.
The illustration shows adipocytes, cells of the adipose tissue, and Trypanosoma brucei parasites that occupy the extracellular spaces between the cells.
Lose the Fat and Curb Parasitic Infection
Mariella Bodemeier Loayza Careaga, PhD | Mar 1, 2024 | 2 min read
Trypanosoma brucei infection induces fat breakdown, but this strategy benefits the host. 
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