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tag genetics genomics histone methylation dna methylation cancer

Concept image of genomic datasets\
Maximizing Biomarker Discovery with the Six-Base Genome
biomodal | Mar 27, 2024 | 1 min read
A multiomic sequencing approach helps scientists capture more biomarker information through liquid biopsy.
Researchers can obtain epigenetic information in addition to genetic insights from a single DNA sample.
The Six-Base Genome Reveals Multimodal Data from a Single DNA Sample
The Scientist and biomodal | Mar 12, 2024 | 4 min read
To gather multiomic insights, researchers used to combine data from multiple workflows, but duet evoC provides more information from less sample in one workflow.
Methylation Sequencing to Identify Potential Cancer Biomarkeres 
Methylation Sequencing in Cancer Detection
The Scientist and Twist Bioscience | Oct 18, 2022 | 1 min read
Discover how efforts to uncover the genome's methylation patterns advance cancer detection.
A view of the nucleus of a cell with DNA in blue, RNA in pink, and associated proteins in yellow and purple
DNA Methylation Influences Replication and Genome Organization
Abby Olena, PhD | Sep 22, 2021 | 3 min read
A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.
Epigenetic Changes Drive Cancer 
Rebecca Roberts, PhD | Nov 28, 2023 | 3 min read
An analysis of almost 700 different tumors revealed that DNA methylation drives tumorigenesis just like genetic mutations do. 
Managing Methylation
Karen Zusi | Jan 1, 2016 | 2 min read
A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.
Chromatogram peaks of a DNA sequencing analysis.
Brush Up: What Is Bisulfite Sequencing and How Do Researchers Use It to Study DNA Methylation?
Deanna MacNeil, PhD | Sep 15, 2022 | 4 min read
Prior to DNA methylation sequencing, researchers treat their samples with sodium bisulfite to distinguish methylated cytosine from unmethylated cytosine.
health care provider standing in front of gynecology stirrups holding swabs for Pap smear
DNA Methylation Could Predict Ovarian, Breast Cancers
Anna Napolitano, PhD | Feb 11, 2022 | 5 min read
A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.
Mapping methylation
Jef Akst | Feb 2, 2010 | 3 min read
With the Human Genome Project largely complete, scientists are turning to variation in the epigenome and beginning to map chemical modifications of DNA that affect gene expression. Two recent studies that provide the first comprehensive maps of human DNA methylation -- one of the most commonly studied epigenetic modifications -- and a new initiative that aims to generate 1,000 more are a testament to this new focus in genetics research. Image: Wikimedia commons, NationalHuman Genome Research In
Composite image showing genes radiating from tumor cells
Jumping Genes’ Role in Cancer
Diana Kwon | Mar 1, 2023 | 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.

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