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Illustration showing how yeast is used to study histone modifications
Infographic: A Yeast Model for Studying Histone Modifications
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Infographic: A Yeast Model for Studying Histone Modifications
Infographic: A Yeast Model for Studying Histone Modifications

The methodology involves modifying histones and displaying them on the cell surface for analysis.

The methodology involves modifying histones and displaying them on the cell surface for analysis.

genetics & genomics, histones

Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021 | 3 min read
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
obituary, obituaries, microbiology, molecular genetics, biochemistry, bioinformatics, Stanford University, University of Southern California, cell & molecular biology
Laurence “Larry” Kedes, Molecular Geneticist, Dies at 83
Amanda Heidt | Apr 26, 2021 | 4 min read
In addition to isolating the first protein-coding gene from a eukaryote, Kedes furthered scientists’ understanding of actin genes and also laid the foundations for modern DNA databases such as GenBank.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
sperm epigenetics cancer risk heritability histones
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Emma Yasinski | Apr 19, 2019 | 3 min read
Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.
As Bees Specialize, So Does Their DNA Packaging
Shawna Williams | Sep 11, 2018 | 3 min read
A study of chemical tags on histone proteins hints at how the same genome can yield very different animals.
Valerie Arboleda Uses Big Data to Unravel the Biology of a Rare Disease
Shawna Williams | May 1, 2018 | 3 min read
The UCLA geneticist examines how defects in a histone protein lead to symptoms throughout the body.
Silencing Surprise
Jenny Rood | Jun 1, 2015 | 2 min read
A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.
Heritable Histones
Ruth Williams | Sep 18, 2014 | 3 min read
Scientists show how roundworm daughter cells remember the histone modification patterns of their parents.
The Epigenetic Lnc
Kevin V. Morris | Oct 1, 2012 | 1 min read
Long non-protein-coding RNA (lncRNA) sequences are often transcribed from the opposite, or antisense, strand of a protein coding gene. In the past few years, research has shown that these lncRNAs play a number of regulatory roles in the cell. For exa
DNA, Contortionist
Kerry Grens | Aug 1, 2012 | 2 min read
The DNA forms known as G-quadruplexes are finally discovered in human cells.
Burning Chromatin at Both Ends
Karen Hopkin | Mar 1, 2009 | 7 min read
Shiv Grewal has seen both late nights and early mornings in the lab – and connections between seemingly disparate elements that other molecular biologists might miss.
Support for histone code?
Brendan Maher | May 21, 2006 | 2 min read
Four papers released online today detail some of the work from David Allis's group and others on chromatin remodeling. 
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