Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.
June 13, 1988|
Iron is both a nutritious and potentially noxious element. Its precise regulation in cells is necessary to assure synthesis of several proteins of which the metal is an integral part. At the same time, the cell must avoid generation of tissue-damaging oxygen radicals, which are known to arise from certain transition metals, such as iron. Environmental iron is mostly in a form (the 3+ oxidation state) that is characterized by extreme insolubility at biological pH. In order to dissolve iron, ma