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» DNA methylation and histones

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image: The Epigenetic Lnc

The Epigenetic Lnc

By | October 1, 2012

Long non-protein-coding RNA (lncRNA) sequences are often transcribed from the opposite, or antisense, strand of a protein coding gene. In the past few years, research has shown that these lncRNAs play a number of regulatory roles in the cell. For exa

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image: Lamarck and the Missing Lnc

Lamarck and the Missing Lnc

By | October 1, 2012

Epigenetic changes accrued over an organism’s lifetime may leave a permanent heritable mark on the genome, through the help of long noncoding RNAs.

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image: Flu Fights Dirty

Flu Fights Dirty

By | September 1, 2012

Mimicking a host-cell histone protein offers flu a sneaky tactic to suppress immune response.

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image: DNA, Contortionist

DNA, Contortionist

By | August 1, 2012

The DNA forms known as G-quadruplexes are finally discovered in human cells.

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image: Combing the Cancer Genome

Combing the Cancer Genome

By | March 1, 2012

A guided tour through the main online resources for analyzing cancer genomics data

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image: Deep Tissue Treatment

Deep Tissue Treatment

By | September 1, 2011

A new, genetically encoded tag for electron microscopy may revolutionize studies of specific proteins in cells and tissues.

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image: First, Do No Harm…

First, Do No Harm…

By | June 9, 2011

Is DNA damage an inevitable consequence of epigenetic reprogramming?

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image: Epigenetic Changes in Cancer

Epigenetic Changes in Cancer

By | March 1, 2011

The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies.

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The Mark of Faith

By | March 1, 2011

Testing a central tenet of epigenetic regulation

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image: Epigenetics and Society

Epigenetics and Society

By | March 1, 2011

Did Erasmus Darwin foreshadow the tweaking of his grandson’s paradigm?

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