DNA methylation

Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.

Altering DNA methylation in a particular area of the hypothalamus halved the animals’ voluntary exercise as adults.

A study suggests that the direct transfer of DNA methylation marks from one generation to the next is much less common than scientists previously thought.

A clock constructed of rDNA methylation sites can estimate both chronological and biological age across species.

Clinical analyses of patients’ gene sequences are helping to provide answers where none were available before.

New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.

Unlike animals, plants stably pass on their DNA methylomes from one generation to the next. The resulting gene silencing likely hides an abundance of phenotypic variation.

Multiple molecular mechanisms keep plant DNA methylation in order.

Researchers attempt to estimate how much of the human genome’s methylation patterns can be attributed to genetic ancestry.

After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.

Plants grown in dry soil produce offspring that are hardier in drought conditions, and DNA methylation appears responsible. 

Three techniques for identifying the collection of maternal and paternal genes silenced in offspring

Methylation on adenine bases is involved in the dampening of gene expression in mammalian cells, according to a study.

Researchers re-examine the evidence for DNA methylation as the cause of behavioral differences among social insects.

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

Moderately obese men display different epigenetic marks on their sperm than lean men, and bariatric surgery in massively obese men correlated with changes in sperm methylation.