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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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From sequencing bacteriophages to synthesizing bacterial genomes to defining a minimal genome

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image: How to Build Bioinformatic Pipelines Using Galaxy

How to Build Bioinformatic Pipelines Using Galaxy

By | August 1, 2016

A point-and-click interface alternative to command-line tools that allows researchers to easily create, run, and troubleshoot serial sequence analyses

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image: On Becoming Human

On Becoming Human

By | August 1, 2016

Some thoughts on going to the Galápagos

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A chloroplast mutation has dramatically affected the genomes of railside populations of Arabidopsis thaliana.

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image: Wanted: Transcriptional Regulators

Wanted: Transcriptional Regulators

By | August 1, 2016

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

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image: Decoding Human Accelerated Regions

Decoding Human Accelerated Regions

By | August 1, 2016

Do the portions of our genomes that set us apart from other animals hold the secret to human evolution?

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image: The Genes Underlying Autism Are Coming Into Focus

The Genes Underlying Autism Are Coming Into Focus

By | August 1, 2016

As researchers sequence the DNA of thousands of kids with autism, dozens of genetic subgroups are emerging.

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image: Contributors

Contributors

By | August 1, 2016

Meet some of the people featured in the August 2016 issue of The Scientist.

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image: A New Way to ID Targets of RNA-Binding Proteins

A New Way to ID Targets of RNA-Binding Proteins

By | July 1, 2016

The catalytic domain of an RNA-editing enzyme is fused with RNA-binding proteins.

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