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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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Researchers solve the mystery of 15-year-old mutant ferns with disrupted sex determination.

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image: Discovering Novel Antibiotics

Discovering Novel Antibiotics

By | February 1, 2017

Three methods identify and activate silent bacterial gene clusters to uncover new drugs

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image: From the Ground Up

From the Ground Up

By | February 1, 2017

Instrumental in launching Arabidopsis thaliana as a model system, Elliot Meyerowitz has since driven the use of computational modeling to study developmental biology.

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The plant Lophophytum pilfers mitochondrial genes from the species it parasitizes.

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image: Characterizing the Imprintome

Characterizing the Imprintome

By | January 1, 2017

Three techniques for identifying the collection of maternal and paternal genes silenced in offspring

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image: How an Invasive Bee Managed to Thrive in Australia

How an Invasive Bee Managed to Thrive in Australia

By | January 1, 2017

The Asian honeybee should have been crippled by low genetic diversity, but thanks to natural selection it thrived.

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image: Methylation Maestro

Methylation Maestro

By | January 1, 2017

After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.

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A test tube-based genome-labeling technique has been brought under the microscope.

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image: RNA Sequences Don’t Predict In Vivo Transcript Structure

RNA Sequences Don’t Predict In Vivo Transcript Structure

By | January 1, 2017

Eukaryotes prevent secondary RNA structures called G-quadruplexes, commonly observed in vitro, from forming in the cell. 

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