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tag genetics genomics histone modification epigenetics

Illustration showing how yeast is used to study histone modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021 | 1 min read
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021 | 3 min read
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
Heritable Histones
Ruth Williams | Sep 18, 2014 | 3 min read
Scientists show how roundworm daughter cells remember the histone modification patterns of their parents.
Two sets of identical twin children sitting
Identical Twins Carry Distinctive Epigenetic Marks: Study
Chloe Tenn | Sep 30, 2021 | 2 min read
Researchers found more than 800 sites in the genome where the twins bore the same chemical tags.
Epigenetics mark regulatory elements
Melissa Lee Phillips | Feb 4, 2007 | 3 min read
Unique histone modifications distinguish transcriptional promoters and enhancers
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
A graphic of two stem cells colored pink and blue splitting from each other, with binary code shown in the background.
Fixing the Problem With Induced Pluripotent Stem Cells
Tanvir Khan, PhD | Oct 31, 2023 | 4 min read
A new strategy prevents reprogramming-induced epigenetic aberrations in human induced pluripotent stem cells.
Modifications Abound
Jeffrey M. Perkel | Aug 1, 2008 | 2 min read
How to conduct your next large-scale epigenetic analysis
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017 | 10+ min read
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.

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