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image: Cell Cannibalism as Cancer Defense

Cell Cannibalism as Cancer Defense

By | July 11, 2017

A new study suggests that the mysterious process by which one cell consumes another may be triggered by cell division, potentially helping to fight tumor growth.

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In two early trials, vaccines tailored to the mutations in individuals’ cancers appeared to protect 12 of 19 patients against relapse. 

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The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  

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image: Sex Reversal Mystery Explained?

Sex Reversal Mystery Explained?

By | June 15, 2017

A proposed mechanism for how bearded dragons with male chromosomes hatch as females at high temperatures

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A new screening tool flags dozens of papers with potential errors.

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The publicly available database found nearly a third of samples included mutations targeted by either approved drugs or therapies in clinical trials. 

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The new findings, obtained from cell culture experiments, could explain the link between infection with the virus during pregnancy and infant microcephaly.

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image: Cell Lines Gain Cancer-Related Mutations

Cell Lines Gain Cancer-Related Mutations

By | April 27, 2017

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

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image: DNA-Based Zika Vaccine Reaches Phase 2

DNA-Based Zika Vaccine Reaches Phase 2

By | April 4, 2017

An NIAID-sponsored clinical trial advances beyond safety testing.

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At the annual American Association for Cancer Research meeting, researchers discuss the importance of understanding the epigenetic contributors to cancer progression and treatment response.

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