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The Nutshell

» cell & molecular biology and clinical trials

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image: Celladon Shutters Its R&D

Celladon Shutters Its R&D

By | June 26, 2015

Biotech firm likely to pull the plug after its gene therapy product fails.

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image: Device Trials Go Unpublished

Device Trials Go Unpublished

By | June 24, 2015

Just half of the clinical studies used to gain premarket approval for cardiac devices ever make it into the scientific literature.

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image: Regenerative Cardiomyocytes Found

Regenerative Cardiomyocytes Found

By | June 24, 2015

Specialized cardiac cells in the mouse heart appear to be the long-sought-after proliferative heart cells.

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image: Extra DNA Base Discovered

Extra DNA Base Discovered

By | June 23, 2015

An epigenetic variant of cytosine is stable in the genomes of living mice, suggesting a possible expansion of the DNA alphabet.

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image: Ebola Drug Trial Terminated

Ebola Drug Trial Terminated

By | June 23, 2015

Early analysis of TKM-Ebola-Guinea offers discouraging results, causing sponsors to end the Phase 2 trial.

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image: The Handedness of Cells

The Handedness of Cells

By | June 17, 2015

Actin—the bones of the cell—has a preference for swirling into a counterclockwise pattern.

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image: Drug for Low Sex Drive in Women?

Drug for Low Sex Drive in Women?

By | June 8, 2015

A federal advisory panel supports the US Food and Drug Administration’s approval of the first drug for female sexual dysfunction.

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image: NIH Halts Drug Production

NIH Halts Drug Production

By | June 8, 2015

The National Institutes of Health’s Pharmaceutical Development Section temporarily suspends production following contamination issues.

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image: NCI Gets Personal

NCI Gets Personal

By | June 2, 2015

The National Cancer Institute is launching a Phase 2 trial matching patients with specific mutations to drugs tailored to those genetic changes.

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image: Viral Immunotherapy for Melanoma

Viral Immunotherapy for Melanoma

By | May 28, 2015

Phase 3 data from a clinical trial show a positive response to a melanoma treatment based on a modified herpesvirus.

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