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RNAi scoops Nobel

By | October 2, 2006

Andrew Z. Fire and Craig C. Mello have won the 2006 Nobel Prize in physiology or medicine for their work in controlling the activity of genes. This is likey to be a welcome award. RNA interference has taken labs by storm and shows some promise in the clinic. More later from The Scientist's news team.

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Introducing Janelia

By | September 29, 2006

The Howard Hughes Medical Institute's new $500 million linkurl:Janelia farm;http://www.hhmi.org/janelia/ campus opens its doors officially next week. This week I toured the main building, which will house 26 labs, during a gathering of HHMI's international researchers. The building is striking. It's shaped like a C and tucked into the side of a hill. The roof is covered with grass and serves as such a convincing meadow that several deer have trotted off the edge. Many of the walls are made of

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Results on islet cell transplants

By | September 28, 2006

In May, James Shapiro linkurl:wrote in our pages;http://www.the-scientist.com/article/display/23394/ about progress using the Edmonton Protocol to transplant islet cells into patients with type 1 diabetes. In this week?s New England Journal of Medicine, he and a number of colleagues around the world linkurl:report the results;http://content.nejm.org/cgi/content/full/355/13/1318 of a phase 1-2 trial of the protocol in 36 patients. The findings were consistent which previous studies that Shapiro d

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Yom Kippur and the Nobels

By | September 28, 2006

On Monday, the Karolinska Institute will announce the 2006 Nobel Prize in Physiology or Medicine, kicking off a week of science Nobel announcements. And millions of Jews around the world will be in synagogue, observing the holiest day of the Jewish calendar, Yom Kippur. Orthodox Jews, and even some Conservative Jews, like my family, don?t answer the phone on the holiday, even if they?re home. So that begs a question: What if an observant Jew is among the winners of the Physiology or Medicine pri

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Metagenomics probes a gutless wonder

By | September 25, 2006

The last week has seen the appearance of two interesting reports on the use of linkurl:metagenomics;http://www.the-scientist.com/article/display/23800/ to probe the biology of microbial communities ? reports that demonstrate the emerging power of this technique to untangle metabolic mysteries in organisms that cannot be grown in the lab. The first, linkurl:published Sept. 17;http://www.nature.com/nature/journal/vaop/ncurrent/abs/nature05192.html in __Nature__, involves the annelid worm, __Olav

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Find out what your candidates think of research

By | September 18, 2006

Research!America today launched the linkurl:2006 Your Candidates ? Your Health Voter Guide;http://www.yourcandidatesyourhealth.org/ -- a site designed to help voters figure out how the candidates seeking their support feel about scientific research. The group sent 10 questions on subjects such as the CDC budget and basic science funding to all House and Senate candidates. To find out how they responded, plug in your zip code. This is an important and timely effort, with the US midterm elections

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Laskers reward telomerase work

By | September 16, 2006

Announced today: The linkurl:2006 Lasker Award;http://www.laskerfoundation.org/ for Basic Medical Research is shared by Elizabeth Blackburn of the University of California, San Francisco, Carol Greider at Johns Hopkins University, and Jack Szostak of Harvard Medical School for their research on telomerase, the enzyme responsible for maintaining the length of linear chromosomes. In addition, Joseph Gall of the Carnegie Institution is being honored for his lifetime of discovery and innovation as

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MAQC Unveils Microarray Magnum Opus

By | September 12, 2006

The microarray research community and industry got a big boost last week with the release by the linkurl:Microarray Quality Control (MAQC) Project;http://www.fda.gov/nctr/science/centers/toxicoinformatics/maqc/ Consortium, of a massive collection of data attesting to the reproducibility and reliability of microarray-based gene-expression profiling. Attempting to lay to rest, once and for all, the question of linkurl:microarray data reliability and reproducibility;http://www.the-scientist.com/a

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Who's up for top WHO job?

By | September 7, 2006

The field candidates for the top job at the World Health Organization is dominated by a list of current and former WHO insiders, it emerged on Wednesday. Of the 13 nominees to fill the post of director general that was linkurl:left vacant;http://www.the-scientist.com/news/display/23475/ earlier this year by the death of Lee Jong-Wook, four currently hold senior WHO posts and three have former connections to the agency. Lee?s unexpected passing in May forced the WHO to put in place an accelera

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A scientist hits the streets

By | September 5, 2006

The photo shoot for this month?s linkurl:feature on the postdoc glut;http://www.the-scientist.com/2006/9/1/42/1/ was obviously a spoof. At least that?s what we thought. Standing on the median of Broad street with a sign that says ?Have PhD, Will Work For Food,? Kevin Duffy expected to garner a few stares, but not much else. ?Some guy gave me his business card,? he told me. Someone walking on the set of the shoot asked what they were doing. Even though Kevin told them they were working on an

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