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Why do clinical science grants lag?

By | July 15, 2008

Applications for grants to fund clinical studies do not fare as well in the linkurl:National Institutes of Health's peer review process;http://www.the-scientist.com/blog/display/54735/ as do those for nonclinical studies, according to an NIH report released yesterday (July 14). The linkurl:report,;http://www.amjmed.com/article/S0002-9343(08)00313-6/fulltext which was conducted by NIH's Center for Scientific Review (CSR) and appears in this month's edition of __The American Journal of Medicine_

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Grassley to APA: Open your books

By | July 14, 2008

Senator linkurl:Charles Grassley;http://www.the-scientist.com/news/display/53381/ (R-IA), ranking member of the Senate Finance Committee, issued a stark warning to the American Psychiatric Association on Thursday (July 10): Clearly outline the pharmaceutical industry's financial influence on your workings or incur my wrath! Well, maybe Grassley didn't use those __exact__ words. "I have come to understand that money from the pharmaceutical industry can shape the practices of non-profit organiza

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Heart surgery pioneer dies

By | July 14, 2008

Michael E. DeBakey, heart surgeon, inventor, teacher, and research advocate, died late last Friday, July 11th, at the age of 99. DeBakey was "the greatest surgeon of the twentieth century," his colleague George Noon said in a linkurl:statement;http://www.methodisthealth.com/tmhs/newsItem.do?channelId=-1073829253&contentId=1073905926&contentType=NEWS_CONTENT_TYPE from Methodist Hospital in Houston, where he spent most of his career. During his 70 years as a surgeon, DeBakey performed over 60,

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Science on the silver screen

By | July 10, 2008

Festooned with jiggling eyeballs, threatening skeletons, and impaled floating heads, Feo Amante's horror thriller linkurl:website;http://www.feoamante.com/ seems an unlikely place to catch up on science. But sandwiched between the "Scary Top 10" and "Big Horror," movie and science buffs alike can check out "Science Moments," short critiques of the use, or lack thereof, of science in film. In 1998, Eddie "Feo Amante" McMullen Jr. started the website as a platform for struggling horror and thrill

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Stem cell prospects dim in NJ

By | July 9, 2008

Can a New Jersey initiative that aims to tap Wall Street money reinvigorate the state's once-ambitious plans for stem cell research? The stem cell research community once had high hopes that New Jersey would become the next California or New York. But in November of last year, the state linkurl:voted against;http://www.the-scientist.com/blog/display/53843/ a linkurl:referendum;http://www.the-scientist.com/news/display/53836/ that would have boosted stem cell research funding by $450 million. N

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Structure hints at Ebola's cunning

By | July 9, 2008

Researchers have determined the crystal structure of the Ebola virus surface protein that binds host cells, they report online today in linkurl:Nature.;http://www.nature.com/nature/index.html The findings open the door to solving the long-standing mystery of the virus's mechanism of infection and designing drugs to combat the deadly hemorrhagic fever caused by linkurl:Ebola.;http://www.the-scientist.com/article/display/22846/ The paper is a "breakthrough," said linkurl:Lijun Rong,;http://www.

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Nature to aid open access

By | July 8, 2008

Nature Publishing Group will begin depositing manuscripts into PubMed Central six months after publication on behalf of authors, starting later this summer, according to a release. But some open access publishing advocates say this is just a way for the publisher to maintain an embargo period, rather than making content immediately available. Earlier this year the National Institutes of Health linkurl:issued a mandate;http://www.the-scientist.com/blog/display/54028/ that required all biomedical

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Subject death halts clinical trial

By | July 8, 2008

A clinical trial for an investigational arthritis drug has been put on hold after a subject in the trial, a bodybuilding father of three with no history of heart problems, suffered two heart attacks and died, the company developing the drug linkurl:announced;http://www.medigene.de/englisch/index_e.php today (July 8). Peter Munro, 48, was participating in a Phase 1 trial for RhuDex, a compound that blocks T-cell activation to prevent inflammation in rheumatoid arthritis, at a clinic outside of

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MD biotechs queue for tax credits

By | July 7, 2008

Representatives from Maryland biotechnology start-ups made like potential contestants for __The Price is Right__ last Monday (June 30) and camped on a Baltimore sidewalk awaiting a chance at success. But these people weren't desperate to participate in the greatest game show on Earth, with a chance to win fabulous cash and prizes. They were lined up for a chance to suckle at the teat of the state's Department of Business and Economic Development, which was passing out state tax credits to biotec

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Visual system surprise

By | July 7, 2008

The soil-dwelling model organism C. elegans, long assumed to lack any visual system whatsoever, in fact appears to be strongly responsive to light, according to a linkurl:paper;http://www.nature.com/neuro/journal/vaop/ncurrent/abs/nn.2155.html published online yesterday (July 6) in Nature Neuroscience. The study identifies four sensory neurons that act as photoreceptor cells driving this phototaxic behavior, and suggests a conservation of phototransduction between vertebrates and worms. "The

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