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Embryonic stem cells still gold standard

By | June 13, 2008

The technical challenges of using retroviruses to reprogram cells to a pluripotent state could be worked out within the year, researchers said today in a press conference at the annual meeting of the International Society for Stem Cell Research in Philadelphia. However, they stressed, human embryonic stem cells are still, and will continue to be, the gold standard for research on pluripotency and differentiation. The speakers, including linkurl:George Daley;http://www.childrenshospital.org/cfap

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Compounds target cancer stem cells

By | June 12, 2008

New compounds that target leukemia stem cells are moving into the clinic this summer. But researchers have yet to pin down exactly how some of these compounds do their job. Today at the International Society for Stem Cell Research's (ISSCR) annual meeting, linkurl:Craig Jordan;http://www.urmc.rochester.edu/GEBS/faculty/Craig_Jordan.htm from the University of Rochester presented his group's recent work on a compound TDZD-8, which was originally developed to inhibit GSK-3, and potentially treat A

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Invitrogen and Applied Biosystems merge

By | June 12, 2008

Biotech company linkurl:Invitrogen;http://www.the-scientist.com/article/display/13263/ announced today (Jun 12) that it will acquire linkurl:Applied Biosystems;http://www.the-scientist.com/article/display/15680/ in a deal valued at $6.7 billion. "This transaction combines the industry's premier consumables provider with the industry's premier systems provider to create a world-class biotechnology tools company," said linkurl:Gregory Lucier,;http://www.biotech360.com/biotechArticleDisplay.jsp?bi

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Stem cell guidelines on the way

By | June 12, 2008

You can now have your say about regulations on bringing stem cell therapies to the clinic. A special task force set up to create guidelines for bringing stem cell therapies from bench to bedside will be accepting public commentary on the guidelines, continuing until this fall, the group announced today at the annual meeting of the International Society for Stem Cell Research (ISSCR) here in Philadelphia. The task force's primary goals are to create guidelines that will help basic researchers

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GSK slashes workforce

By | June 11, 2008

In another move to encourage innovation while trimming its research and development budget, pharmaceutical company GlaxoSmithKline has announced that it will cut two percent, or 350 jobs, from its global R&D staff, according to linkurl:__The Wall Street Journal__.;http://online.wsj.com/article/SB121318410957563897.html?mod=hps_us_at_glance_health "These changes are part of GSK's longer-term strategy to ensure that we invest in key areas of future growth and evolve our business to compete effect

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Senate tweaks bioterror regs

By | June 11, 2008

The US Senate today (June 11) plans to introduce a biosafety bill that takes small steps towards resolving some controversial aspects of the system regulating research with agents that could be used for bioterrorism. The regulations, called the Select Agent Program, have been controversial since they were established in 2002. Researchers have said that the rules linkurl:created red tape;http://www.the-scientist.com/article/display/14717/ that stymied research, hindered international collaborati

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Trees have internal thermostat

By | June 11, 2008

Trees from the linkurl:Caribbean;http://www.the-scientist.com/article/display/53628/ to linkurl:Canada;http://www.the-scientist.com/article/display/15054/ maintain a constant leaf temperature regardless of the ambient air temperature, according to a new study by researchers at the University of Pennsylvania. The findings could dramatically alter interpretations of data used to approximate past climate from the composition of tree rings, the researchers say. Scientists who measure cellulose com

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Big pharma gets creative

By | June 10, 2008

With blockbuster drug patents set to expire in the next few years, big pharma is looking hard for ways to pack the discovery pipeline. One approach: the biotech model. Patrick Vallance, the head of drug discovery at GlaxoSmithKline, said at a meeting on Friday (June 6) that research at the company would be reorganized to be "more biotech-like," the Financial Times linkurl:reported.;http://www.ft.com/cms/s/0/a36193c0-366e-11dd-8bb8-0000779fd2ac.html?nclick_check=1 He said the plan was to split

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Fauci at the UN

By | June 10, 2008

linkurl:Anthony Fauci,;http://www.the-scientist.com/article/display/13734/ director of the NIH's National Institute of Allergy and Infectious Diseases (NIAID), addressed the United Nations General Assembly in New York City today (Jun 10), telling delegates and dignitaries that the key to controlling HIV/AIDS in developing nations is prevention, and especially the development of linkurl:vaccine;http://www.the-scientist.com/blog/display/54655/ for the disease. Fauci said that "a preventive HIV va

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FDA investigators banned

By | June 10, 2008

The Food and Drug Administration has disqualified seven investigators so far this year for misconduct, according to an linkurl:FDA document.;http://www.fda.gov/ora/compliance_ref/bimo/disqlist.htm The ruling bars the doctors from conducting clinical trials of any kind. The FDA, for reasons including submitting false information to the trial's sponsor or the FDA, or not complying with regulatory requirements, has disqualified more than 100 investigators from clinical trials over the past 40

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