cancer, cell & molecular biology

Principal Investigator, Whitehead Institute for Biomedical Research. Associate Professor, Department of Biology, Massachusetts Institute of Technology. Age: 44

A single mutant cell breaks free of its neighbors in the early stages of cancer development.

Chromosomes accidentally stranded outside of the nucleus could contribute to cancer formation.

Certain skin-residing immune cells may—under specific conditions—play a direct role in initiating skin cancer after exposure to environmental toxins.

Assistant Professor, Department of Anatomy and Cell Biology, University of Western Ontario. Age: 34

The age at which BRCA carriers are diagnosed with breast cancer may depend on which parent contributed the mutation.

Researchers have developed a way to activate cancer fighting drugs by pulsing them with light, which could make such therapies safer.

An alternative form of an enzyme involved in the glucose metabolism pathway protects cancer cells from oxidative stress.

Researchers have pinpointed the region of a key cancer gene that’s involved in tumor suppression.

Researchers show that errors in chromosome segregation known to cause chromosome instability can also lead to gene translocations, insertions, or deletions.

Cellular structures known as midbodies, formed during cell division, appear to accumulate in stem cells and cancer cells, hinting at a potential function for these once-disregarded organelles.

Caffeinated drinks may help prevent skin cancer by inhibiting a DNA repair pathway, thus killing potentially precancerous cells.

Sheng Wang leaves the Boston University School of Medicine and agrees to retract two published studies.

Using the strongest molecular binding partnership in biology to separate different cell types.

For more than 100 years, pathologists have observed cancer cells engulfing other live cells, but scientists are only now beginning to understand how it happens and what it means for tumorigenesis.

Isolating specific cell types from a mass of plant or animal tissue is laborious and tricky. 

A snapshot of the most highly ranked articles in genomics, genetics, and related areas, from Faculty of 1000

Free radicals, widely believed to promote cancer, may actually slow tumor growth.

A snapshot of the most highly ranked articles in cancer biology and related areas, from Faculty of 1000

Ovarian tumor cells use cellular movement proteins to penetrate protective cell layers surrounding new target tissues during metastasis.