cancer

See some of the coolest images recently featured by The Scientist

Notes from my first in-person mega-conference in two years

Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.

Nanoparticle-coated bacteria can capture tumor antigens and deliver them to immune cells, triggering a response that improved survival rates in mice.

Nanoparticle-coated bacteria carry cancer-derived proteins to dendritic cells, enabling the immune system to launch a response in a mouse model.

Self-inflicted DNA breaks let the cells hit pause on repair of radiation-induced DNA damage, giving them time to recover, an in vitro study shows.

Analyzing the whole genome sequences of more than 18,000 tumors, researchers catalog nearly 60 new patterns of mutations that could inform cancer treatment.

In vitro and mouse experiments show how cancer cells forced through tiny pores—mimicking the physical experience of metastasis—resisted programmed cell death and avoided detection by the immune cells that would normally kill them.

Observational evidence for the connection is solidifying, and some clues are emerging about the mechanisms that may explain it.

New research in mice reveals why natural killer cells, normally effective at hunting cancer, are sometimes stopped in their tracks.  

The unique odor profiles of tumors can be used to develop diagnostic sensing tools.

A collaboration between friends led to a cautionary finding about CRISPR’s effect on cells.

Microbes designed to produce specific immunomodulatory metabolites could give immunotherapy a boost.

Rounds of trial-and-error exploring the layer of cells covering the ovary leave open questions about stem cells that are associated with ovarian cancer.