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DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Lasker Award winner Piet Borst sits at his desk.
A Journey With Metabolism, Parasites, and Cancer
Laura Tran, PhD | Sep 21, 2023 | 7 min read
Piet Borst led stellar work on cell organelles, trypanosomes, and cancer drug resistance during the golden age of biology.
Zebrafish with fluorescent nervous system in green.
Oust the Mouse: A Plan to Reduce Mammal Use in Drug Development
Natalia Mesa, PhD | Mar 15, 2022 | 7 min read
The Scientist spoke to Mount Desert Island Biological Laboratory’s Jim Strickland about the institute’s new MDI Bioscience initiative to perform more drug testing and development in nonmammalian models.
Molecular Approaches Breathe New Life Into Sports Medicine
Sara Latta | Jul 20, 1997 | 7 min read
Now that summer is in full swing, all but the most dedicated couch potatoes are playing on departmental softball teams, hitting the tennis courts, or laboring in the garden. For a growing number of scientists, however, exercise is more than a seasonal diversion-it's the focus of a thriving discipline that integrates molecular and cellular biology, physiology, nutrition, and behavioral sciences. One important trend, not only in exercise science but also in physiology, is the integration of mole
Image of pancreatic organoids under a microscope with immunofluorescent staining
Pancreatic Organoids Take the Stage
Laura Tran, PhD | Dec 1, 2023 | 2 min read
Meritxell Huch tackled her pipedream of growing three-dimensional pancreatic tissue in a dish.
Environmental Health Institute Blends Toxicology And Molecular Biology
Karen Young Kreeger | May 1, 1995 | 9 min read
Situated equidistant from Raleigh, Durham, and Chapel Hill, N.C.--smack in the middle of the Research Triangle--sits the only National Institutes of Health institutional campus outside of the Washington, D.C., Beltway. The National Institute of Environmental Health Sciences (NIEHS) is currently responsible for nearly 50 percent of all federally funded research on such subjects. It commands a diverse research agenda that covers populations and geographical boundaries far beyond the triangle or t
A Geneticist’s Quest to Understand His Son’s Mysterious Disease
Tracie White | Jan 1, 2021 | 4 min read
Ronald Davis of Stanford University changed his focus to research on ME/CFS, the disease formerly known as chronic fatigue syndrome, in a bid to help his son and others like him.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.

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