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Exploring the Matrix: A Profile of Zena Werb
Exploring the Matrix: A Profile of Zena Werb
The cell and molecular biologist unveiled a role for the breakdown of proteins in the extracellular matrix in both healthy and pathogenic cells.
Exploring the Matrix: A Profile of Zena Werb
Exploring the Matrix: A Profile of Zena Werb

The cell and molecular biologist unveiled a role for the breakdown of proteins in the extracellular matrix in both healthy and pathogenic cells.

The cell and molecular biologist unveiled a role for the breakdown of proteins in the extracellular matrix in both healthy and pathogenic cells.

disease & medicine, cancer

CRISPR-Edited T Cells Used in Cancer Patients for the First Time in the US
Emily Makowski | Nov 6, 2019 | 2 min read
The initial findings from a small clinical trial of patients with multiple myeloma or sarcoma suggest that gene-edited immunotherapy is safe.
Image of the Day: Patient-Derived Organoids
Emily Makowski | Oct 10, 2019 | 1 min read
Three-dimensional tissue cultures grown from cancer patients’ own tumors can predict responses to the drug irinotecan.
Aggressive Cancers Feed Off the Brain’s Nerves
Emily Makowski | Sep 20, 2019 | 2 min read
Three studies show that tumor cells can behave like neurons.
State Marijuana Legalization Aids Research Very Little
Ashley Yeager | Sep 20, 2019 | 7 min read
Recent federal announcements serve as reminders that in the US policy continues to outpace science when it comes to cannabis.
an illustration of dividing cancer cells
Cancer Drugs in Development May Be Targeting Wrong Proteins
Shawna Williams | Sep 12, 2019 | 3 min read
A study of 11 drugs now in clinical trials suggests they do kill cancer cells—but through a different mechanism than indicated in previous research.
Cigall Kadoch Unravels Chromatin’s Role in Cancer
Chia-Yi Hou | Sep 1, 2019 | 3 min read
The Dana-Farber Cancer Institute researcher is developing cancer therapeutics based on how the physical structure of DNA contributes to the disease.
tweaking microbiome composition reduces colorectal tumor growth in mice
Image of the Day: Tamed Gut Bacteria
Nicoletta Lanese | Aug 8, 2019 | 2 min read
Curbing the growth of harmful bacteria in mouse microbiomes reduces the animals’ incidence of inflammation-related colorectal cancer.
Virologist Keerti Shah Dies
Catherine Offord | Aug 2, 2019 | 3 min read
The Johns Hopkins University researcher’s work helped solidify the link between human papillomavirus and cervical cancer, leading to the approval of the HPV vaccine in 2006.
Hydrogel injected near tumors help recruit cancer drugs to the site
Image of the Day: Right on Target
Nicoletta Lanese | Jul 23, 2019 | 1 min read
An injectable biomaterial calls cancer drugs to tumor sites in mice.
smart pills
Smart Pills Help Monitor Cancer Patients’ Therapy
Chia-Yi Hou | Jul 15, 2019 | 5 min read
Sensors encapsulated with oral chemotherapy drugs help patients and physicians keep track of treatments.
Contributors july august the scientist
Contributors
The Scientist | Jul 15, 2019 | 3 min read
Meet some of the people featured in the July/August 2019 issue of The Scientist.
Mardis on the Future of Clinical Genomics
The Scientist | Jul 15, 2019 | 1 min read
Meet researcher Elaine Mardis of the Institute for Genomic Medicine at Nationwide Children’s Hospital in Ohio and coauthor of a feature article on cancer vaccines.
3-D Treatment
Tumor Organoids Hold Promise for Personalizing Cancer Therapy
Jef Akst | Jul 15, 2019 | 4 min read
The three-dimensional cell cultures are still in the development phase, but researchers are excited about their use to predict patients’ responses to various treatment options.
Organoids grown from a mouse’s colon
Caught on Camera
The Scientist | Jul 15, 2019 | 1 min read
Selected Images of the Day from the-scientist.com
scientist to watch laura bowers
Laura Bowers Works to Sever the Link Between Obesity and Cancer
Shawna Williams | Jul 15, 2019 | 3 min read
The Purdue University nutrition researcher delves into the details of how fat tissue affects tumors.
Chronic lymphocytic leukemia
T Cell Proliferation Linked to CAR T Responses
Ashley Yeager | Jul 15, 2019 | 2 min read
Comparing the cells of cancer patients who did and did not respond to the immunotherapy could reveal biomarkers to predict who should receive it in the first place.
personalized vaccines
Infographic: Neoantigen Prediction for Personalized Vaccine Design
Jasreet Hundal and Elaine R. Mardis | Jul 15, 2019 | 3 min read
See how a computational pipeline uses next-generation sequencing data to identify genetic alterations that produce cancer-specific antigens.
custom targeted cancer vaccine
Personalized Cancer Vaccines in Clinical Trials
Jasreet Hundal and Elaine R. Mardis | Jul 15, 2019 | 10+ min read
The field is young, but predicting antigens produced by patients’ malignant cells could yield successful treatments for individuals with a range of cancer types.
Does the Microbiome Help the Body Fight Cancer?
Catherine Offord | Jul 10, 2019 | 4 min read
Research in mice and humans is beginning to establish a link between the composition of microbes in the gut and immune responses to tumor cells, but the mechanisms are not yet clear.
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