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genetics & genomics

Infographic: Keeping RNA Structures in Line
Catherine Offord | Dec 31, 2016 | 1 min read
Scientists find fewer RNA G-quadruplexes in vivo than in vitro.
More Anti-CRISPR Proteins to Block Cas9
Kerry Grens | Dec 29, 2016 | 2 min read
The latest CRISPR deactivators to be discovered turn off the Streptococcus pyogenes Cas9 widely used in genome editing.
Exome Study Reveals Novel Disease-Linked Alleles
Anna Azvolinsky | Dec 22, 2016 | 4 min read
By combining whole-exome sequencing data with longitudinal electronic health record information for 50,000 individuals, researchers have identified novel disease associations.
New Species of 2016
Jef Akst | Dec 16, 2016 | 3 min read
From a new Tyrannosaurus and many other dinosaurs to all of the living species named this year, researchers continue to chip away at the planet’s unknown biodiversity.
Slideshow: New Species of 2016
Jef Akst | Dec 16, 2016 | 1 min read
A look at some of the species named this year
Induced Pluripotent Stem Cells Show Signs of Donor Age
Ashley P. Taylor | Dec 12, 2016 | 3 min read
iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.
Phages Carry Antibiotic Resistance Genes
Abby Olena, PhD | Dec 7, 2016 | 2 min read
Researchers find evidence of antibiotic resistance genes in the DNA of viruses that infect bacteria.
Vlad Denic on Exploring New Fields and Failing Successfully
Ben Andrew Henry | Dec 1, 2016 | 3 min read
The Harvard professor is pursuing fundamental questions about autophagy, protein homeostasis, and other cellular processes, and he’s always on the lookout for his next new topic.
Opinion: Not All Genetic Databases Are Equal
Charles M. Strom | Dec 1, 2016 | 4 min read
Sorting out which data sets are clinical-grade is key to helping patients.
The Pangenome: Are Single Reference Genomes Dead?
Catherine Offord | Dec 1, 2016 | 10+ min read
Researchers are abandoning the concept of a list of genes sequenced from a single individual, instead aiming for a way to describe all the genetic variation within a species.
Infographic: Partitioning the Genome
Catherine Offord | Nov 30, 2016 | 1 min read
To make sense of the genetic variation within species, researchers are turning to the concept of the pangenome.
Genome Digest
Ben Andrew Henry | Nov 23, 2016 | 4 min read
What researchers are learning as they sequence, map, and decode species’ genomes
Researchers Propose Solution to Gene Drive Technology Problem
Ben Andrew Henry | Nov 22, 2016 | 1 min read
Scientists are getting to closer to developing a technique that can suppress mosquito populations on a continental scale, based on preliminary modeling results.
Scientists Can’t Replicate Gene-Editing Method
Kerry Grens | Nov 20, 2016 | 2 min read
Even with the original authors’ vector, the NgAgo technique doesn’t work in others’ hands.
Virus Provides Clues About Geography
Amanda B. Keener | Nov 18, 2016 | 2 min read
Researchers use genotypes of a virus commonly found in semen to trace men’s geographic origins.
Mutation vs. Mutation
Kerry Grens | Nov 3, 2016 | 1 min read
Yeast study finds many instances—often among related genes—in which a mutation in one gene cancels the negative effects of a mutation in another.
Smoking-Linked Cancer Mutations Mapped
Anna Azvolinsky | Nov 3, 2016 | 3 min read
Scientists produce a detailed genomic map of mutations and epigenetic changes associated with smoking tobacco across 17 tumor types. 
How These Rodents Got Their Stripes
Ashley P. Taylor | Nov 2, 2016 | 3 min read
The African striped mouse and the chipmunk develop dorsal stripes through a newly identified mechanism of coat color variation.
Genotyping “Surrogates” Misdiagnoses Deadly Heart Condition
Kerry Grens | Nov 2, 2016 | 2 min read
Family members with a certain gene variant had unnecessary interventions, highlighting the potential hazards of precision medicine.
Social Media Accelerates Science
Ben Andrew Henry | Nov 1, 2016 | 6 min read
How researchers are taking advantage of Twitter and other forums to do, share, and discuss research
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