genetics & genomics

Raphael Weldon’s critiques of Mendelian principles were 100 years ahead of his time.

Fifteen years after publication of the human genome’s first draft sequence, what has become of the hundreds of researchers who worked on the project?

Associate Professor, Virginia Tech, Department of Forest Resources and Environmental Conservation. Age: 37

Meet February profilee Natasha Raikel and hear her explain why studying plant genetics is crucial.

Increasing the expression of two genes from non-Y chromosomes restores spermatogenesis in male mice that lack Y chromosomes.

Genetic evidence suggests that overactive synaptic pruning drives development of schizophrenia.

Researchers at the University of California, Berkeley, boost the CRISPR/Cas9 system’s gene-editing success rate in short pieces of DNA.

Genetically modified bacteria that don’t survive unless given an unnatural amino acid could serve as a new control measure to protect wild organisms and ecosystems against accidental release. 

Key Alzheimer’s disease–related protein may be a transcriptional regulator.

A Brazilian town will ramp up the release of insects engineered to shrink mosquito populations.

One of three suspect publications from a group of scientists in Italy is pulled for plagiarism while an investigation is ongoing.

The boards of both companies have agreed to a $1.3 billion deal, which is subject to Affymetrix shareholder approval.

Many patients with genetic variations linked to cardiac disorders do not exhibit any symptoms, raising concerns about the validity of incidental findings of genetic tests.

A challenge to the first CRISPR patent just got teeth.

Three groups of researchers used the gene-editing method to restore a protein deficient in Duchenne muscular dystrophy.

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.

Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.

January 2016's selection of notable quotes

Understanding the biological roots of cooperation might help resolve some of the biggest scientific challenges we face.

Meet some of the people featured in the January 2016 issue of The Scientist.