The new technique reveals unprecedented details of microscopic life.
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Long non-protein-coding RNA (lncRNA) sequences are often transcribed from the opposite, or antisense, strand of a protein coding gene. In the past few years, research has shown that these lncRNAs play a number of regulatory roles in the cell. For exa
Isolating specific cell types from a mass of plant or animal tissue is laborious and tricky. To study epigenetic changes and genes that are expressed differently in different cell lineages—such as cancer cells versus normal cells, or the two types of
Using synchrotron rapid scanning X-ray fluorescence to map the distribution of trace metals in avian fossils over 120 million-year-old, researchers reconstruct the pigment patterns of their feathers—revealing some of the extinct birds' long-lost colo
The optogenetic toolset is composed of genetically encoded molecules that, when targeted to specific neurons in the brain, enable the electrical activity of those neurons to be driven or silenced by light. When these opsins are expressed in the lipid
Take a tour of the Linac Coherent Light Source (LCLS), whose ultra-powerful X-ray beam is being used to solve the structures of proteins that are notoriously hard to crystallize.
This animation illustrates optogenetics—a radical new technology for controlling brain activity with light. Ed Boyden, the co-inventor of this technology, is a professor at the MIT Media Lab and at the McGovern Institute for Brain Research, where he continues to develop new technologies for controlling brain activity.
A powerful new X-ray–generating laser is imaging smaller crystals than ever before.
Epigenetic events regulate the activities of genes without changing the DNA sequence. Different genes are expressed depending on the methyl-marks attached to DNA itself and by changes in the structure and/or composition of chromatin. The main compone
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