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an illustration of a single cell with a backdrop of similar cells
The Advances that Will Shape Life Sciences in the 2020s
Emma Yasinski | Jan 3, 2020 | 3 min read
Systems biologist Steven Wiley says advancements in two areas—single-cell biology and CRISPR—are poised to transform research.  
Image of the Day: Patient-Derived Organoids
Emily Makowski | Oct 10, 2019 | 1 min read
Three-dimensional tissue cultures grown from cancer patients’ own tumors can predict responses to the drug irinotecan.
3-D Treatment
Tumor Organoids Hold Promise for Personalizing Cancer Therapy
Jef Akst | Jul 15, 2019 | 4 min read
The three-dimensional cell cultures are still in the development phase, but researchers are excited about their use to predict patients’ responses to various treatment options.
MyHeritage Launches Health-Related Genetic Test, Ignites Debate
Catherine Offord | Jul 9, 2019 | 8 min read
Its screen for selected variants of some disease-linked genes gives customers an incomplete picture of their risk—do they know?
artificial intelligence feature the scientist
AI Uses Images and Omics to Decode Cancer
Amber Dance | May 1, 2019 | 10 min read
Machine learning can analyze photographs of cancer, tumor pathology slides, and genomes. Now, scientists are poised to integrate that information into cancer uber-models.
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Carolyn Wilke | Apr 1, 2019 | 3 min read
Computational biologist Jinghui Zhang of St. Jude realized scientists could work more efficiently with tools and genomic data shared on the cloud.
lab tools cancer therapy
Contending with Resistance in Cancer Immunotherapy
Marissa Fessenden | Apr 1, 2019 | 7 min read
Researchers describe ways to study how cancer cells evade therapies that harness the immune system.
Top Technical Advances in 2018
Shawna Williams | Dec 23, 2018 | 3 min read
The year’s most impressive achievements include ecology research via drone, mice with two dads, and the use of artificial intelligence to identify and monitor cancer cells.
Image of the Day: Bad Behavior
Kerry Grens | Dec 12, 2018 | 1 min read
A deep learning program can identify cells with higher metastatic potential based on the way they look and move.
Breakthrough Prizes Recognize Aneuploidy Researcher, Biochemist
Catherine Offord | Oct 18, 2018 | 2 min read
This year’s winners also include the developers of nusinersen, an oligonucleotide therapeutic for spinal muscular atrophy.
CRISPR Gene Editing Deletes, Shuffles More Genes than Intended
Ashley Yeager | Jul 16, 2018 | 2 min read
The DNA-cutting enzyme used in the technique is not as precisely targeted as scientists had thought, and investors take notice.
Traitorous Tumor Cells Kill Their Own Kind
Ruth Williams | Jul 11, 2018 | 3 min read
Researchers plan to turn cancer cells into defectors, engineering them to kill the tumors from whence they came, and have tested the approach in mice.
Opinion: Deductive Science Is Needed for Public Health
Giuseppe Carruba | Jun 27, 2018 | 3 min read
Big data and empirical approaches to understanding diseases provide a limited picture of pathogenesis.
Artificial Intelligence to Boost Liquid Biopsies
Claire Asher | Jun 26, 2018 | 4 min read
Machine-learning algorithms tuned to detecting cancer DNA in the blood could pave the way for personalized cancer care.
CRISPR Efficiency Tied to Cancer-Causing Process
Kerry Grens | Jun 11, 2018 | 2 min read
Two studies find the genome-editing technique works best when cells have a faulty DNA-damage response that’s frequently present in cancers.  
Immunotherapy More Effective in Men: Study
Kerry Grens | May 18, 2018 | 2 min read
Women with metastatic cancer who were treated with a checkpoint inhibitor had a smaller benefit than did men.
Big Data in 3 Dimensions
Jim Daley | May 1, 2018 | 2 min read
Viewing oncogenic mutations in 3-D showed that they cluster together on folded proteins.
Pinpointing the Culprit
Rachel Berkowitz | Jun 1, 2017 | 8 min read
Identifying immune cell subsets with CyTOF
Targeting Tregs Halts Cancer’s Immune Helpers
Ruth Williams | Apr 1, 2017 | 2 min read
New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.
Infographic: Antibody Cancer Therapy
Ruth Williams | Mar 31, 2017 | 1 min read
An experimental technique removes T cells that aid in vitro tumor growth.
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