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Dead shark on concrete
Researchers Make Alternatives to Shark-Sourced Vaccine Ingredient
Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.
Researchers Make Alternatives to Shark-Sourced Vaccine Ingredient
Researchers Make Alternatives to Shark-Sourced Vaccine Ingredient

Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.

Synthetic variations of squalene, which is used to boost immune responses, could make vaccines more effective while reducing fisheries for struggling sharks.

vaccine, immunology

A triangular sign affixed to a tree displaying the silhouette of a tick.
Newly Developed mRNA Vaccine Protects Against Lyme Disease
Charlene Lancaster, PhD | Nov 13, 2023 | 5 min read
Leveraging the same mRNA platform used for COVID-19 vaccines, researchers generated a vaccine that prevents mice from acquiring Lyme disease.
RSV vaccine design concept art
RSV Vaccines That Work?
Rachael Moeller Gorman | Feb 16, 2023 | 10+ min read
Multiple candidates are in Phase 3 clinical trials for older adults and pregnant women, with some getting close to approval in the United States.
New Strategies in the Battle Against Infectious Diseases
New Strategies in the Battle Against Infectious Diseases
The Scientist Staff | 2 min read
Learn how the latest research into viral and bacterial pathogens advances the prevention and treatment of infectious diseases. 
Fluorescence image in purple and green of lymph node
Targeting Antigen “Sanctuary” in Lymph Nodes Could Make Vaccines Better
Natalia Mesa, PhD | Feb 10, 2023 | 3 min read
Researchers find that small sacks inside lymph nodes contain low proteolytic activity and act as safe havens for antigens.
Sam Katz looks at the camera
Measles Vaccine Developer Samuel Katz Dies at 95
Lisa Winter | Nov 23, 2022 | 3 min read
He also worked on immunizations against polio, rubella, influenza, and more.
Beyond Cytotoxicity: The Importance of T Cell Memory<br ><br>
Beyond Cytotoxicity: The Importance of T Cell Memory
The Scientist | 1 min read
In this webinar, Grégoire Lauvau and Marcus Buggert will discuss the function and role of memory T cells in health and disease.
person in white jacket putting bandaid on arm of child
Can We Predict How Well Someone Will Respond to a Vaccine?
Natalia Mesa, PhD | Nov 14, 2022 | 7 min read
Researchers find signatures pre- and post-vaccination that correlate with a more robust immune response. 
Illustration showing immunology during pregnancy
Infographic: How Immunology Can Influence Pregnancy Outcomes
Tobias R. Kollmann, Arnaud Marchant, and Sing Sing Way | Nov 14, 2022 | 3 min read
Pregnancy-induced changes in the immune system are key to a successful birth. Understanding those changes could allow researchers to protect both mother and child.
<em >The Scientist</em>&rsquo;s Journal Club: Immunology
The Scientist’s Journal Club: Immunology
The Scientist | 1 min read
Scientists present the latest research on the immune response against SARS-CoV-2, the influence of COVID-19 on future vaccine responses, and drivers of T cell development.
Illustration of pregnancy and the immune system
Modulating Immunity to Improve Pregnancy Outcomes
Tobias R. Kollmann, Arnaud Marchant, and Sing Sing Way | Nov 14, 2022 | 10+ min read
Aberrant immune activation, the main cause of prematurity and stillbirths, could be preventable through interventions such as maternal vaccination. 
A person in a white shirt activates a nasal spray
Oxford-AstraZeneca Nasal COVID-19 Vaccine Falters in Clinical Trial
Dan Robitzski | Oct 11, 2022 | 2 min read
Researchers say they’re abandoning the project in its current form—one of several that aims to induce what’s known as mucosal immunity against SARS-CoV-2.
Discover new treatments for pandemic diseases
Treatments for Disease Pandemics
The Scientist | 1 min read
Researchers develop new vaccines and therapeutics to combat the spread of infectious diseases.
A germinal center inside a lymph node
Slow Vaccine Delivery May Maximize Immune Response
Alejandra Manjarrez, PhD | Sep 23, 2022 | 5 min read
A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez, PhD | Sep 15, 2022 | 4 min read
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
T Cells: A New Hope for Lasting Protection against SARS-CoV-2
The Scientist | 1 min read
Alessandro Sette and Shane Crotty discuss the T cell response to SARS-CoV-2 and the implications for vaccine design and robust immune memory.
Artist’s rendition of light blue monkeypox viruses in front of a black background.
FDA To Stretch Monkeypox Vaccine Supply via Intradermal Injection
Shafaq Zia | Aug 12, 2022 | 4 min read
The newly authorized intradermal vaccination only requires one-fifth of the usual vaccine dose. This will help stretch out the limited vaccine supply, experts say, but only if healthcare personnel receive sufficient training.
Man in lab coat looking at the camera and smiling
Can Taking a Test Now Tell You if You’ve Already Had COVID-19?
Natalia Mesa, PhD | Aug 8, 2022 | 4 min read
The Scientist asks Brigham and Women’s Hospital infectious disease specialist Lindsey Baden about testing for prior infections.
COVID-19 vaccine vials
COVID-19 Vaccines Induce Better Long-Term Immunity than Infection
Jennifer Zieba, PhD | Aug 8, 2022 | 3 min read
For the first time, researchers performed a head-to head longitudinal study comparing the immune response elicited by mRNA and traditional COVID-19 vaccines to primary infections.
Illustration of a syringe with a person falling out of a bottle of pills
Opioid Vaccines as a Tool to Stem Overdose Deaths
Tori Rodriguez | Jun 13, 2022 | 10+ min read
Researchers are turning to the immune system for help in treating addiction and preventing overdose.
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