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» genetics, cancer and antibiotic resistance

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image: Blue Biotech

Blue Biotech

By | March 1, 2013

Systems biologist Lone Gram describes her approach to combing the oceans for novel compounds that may be useful in the fight against pathogens.

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image: The Plastid Gene Shuffle

The Plastid Gene Shuffle

By | January 1, 2013

How plastid genetic information survived (or didn’t) the endosymbiotic experience

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image: 2012 Labbies Honorable Mentions

2012 Labbies Honorable Mentions

By | October 1, 2012

Check out other memorable images and videos that were submitted to this year’s Labby Multimedia Awards.

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image: Telomere Basics

Telomere Basics

By | May 1, 2012

Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. Telomeres protect the protein-coding sequences of DNA on

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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. In order to replicate the structure of an enzyme’s transition state, whic

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image: Suspected Effects of Vitamin D

Suspected Effects of Vitamin D

By | March 1, 2012

Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. Through this mechanism, vitamin D promotes calcium absorption

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image: Teen DNA Detectives

Teen DNA Detectives

By | December 1, 2011

Genomicist Mark Stoeckle and three high school students have taken do-it-yourself science to a new level. Research headquarters are Stoeckle’s Upper West Side apartment, where he’s laid out pipettes, a thermocycler, and a gel reader in the spots usua

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image: Designing Genetic Circuits

Designing Genetic Circuits

By | October 1, 2011

Near the turn of the millennium, James Collins and Stanislas Leibler independently undertook rather similar projects: design what would become synthetic biology’s seminal genetic circuits. And they came up with strikingly similar action plans—use E.

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image: Swallowing the Surgeon

Swallowing the Surgeon

By | October 1, 2011

In fewer than 15 years, nanomedicine has gone from fantasy to reality.

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image: The Right Sort

The Right Sort

By | August 1, 2011

Isolating specific cell types from a mass of plant or animal tissue is laborious and tricky. To study epigenetic changes and genes that are expressed differently in different cell lineages—such as cancer cells versus normal cells, or the two types of

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