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» epigenetics and brain

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image: Cortex Tour

Cortex Tour

By | November 1, 2013

Travel through the outer layers of a mouse brain thanks to array tomography and Stanford University's Stephen Smith.

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image: Lozano on DBS

Lozano on DBS

By | November 1, 2013

Neurosurgeon Andres Lozano discusses deep-brain stimulation in this TEDx talk.

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image: Mental Clarity

Mental Clarity

By | November 1, 2013

Karl Deisseroth and his team at Stanford University make mouse brains transparent to explore their inner workings.

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image: The Epigenetic Lnc

The Epigenetic Lnc

By | October 1, 2012

Long non-protein-coding RNA (lncRNA) sequences are often transcribed from the opposite, or antisense, strand of a protein coding gene. In the past few years, research has shown that these lncRNAs play a number of regulatory roles in the cell. For exa

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image: Lost in Space

Lost in Space

By | September 1, 2011

Looking for a more realistic way to study memory, we turned to place cells­­—­a network of cells that record a rat’s memory of an environment. 

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image: The Seat of Memory

The Seat of Memory

By | September 1, 2011

Early on, researchers had learned that the hippocampus was the structure in the brain where long-term memories were created and stored, but it was not known whether the different cell types within this structure might be more or less susceptible to the aging process.

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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

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image: The Right Sort

The Right Sort

By | August 1, 2011

Isolating specific cell types from a mass of plant or animal tissue is laborious and tricky. 

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image: Epigenetics—A Primer

Epigenetics—A Primer

By | March 1, 2011

Epigenetic events regulate the activities of genes without changing the DNA sequence. Different genes are expressed depending on the methyl-marks attached to DNA itself and by changes in the structure and/or composition of chromatin. 

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