Sangamo Biosciences is putting a different spin on gene therapy. Rather than replace or supplement a mutated gene with an accurate copy, Sangamo researchers are introducing a mutant copy of the gene for the HIV co-receptor CCR5 into the T cells of HI
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Among the naked mole-rat’s amazing qualities is the reduced ability to feel certain kinds of pain, such as that caused by acids—including the acid produced by high concentrations of carbon dioxide (CO2)—and capsaicin (the spicy compound found in chil
Check out the 10 images that won FASEB's first annual Bio-Art competition.
It’s a well-known story: The peppered moth’s ancestral typica phenotype is white with dark speckles. In the decades following the Industrial Revolution, a new, soot-colored form, known as carbonaria, flourished and displaced the typica moths in the h
Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. Telomeres protect the protein-coding sequences of DNA on
A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. In order to replicate the structure of an enzyme’s transition state, whic
Researchers are permanently marking endangered reptiles in Madagascar to keep the animals from entering the illegal wildlife trade. Read the full story. [gallery]
During development, the cells of an embryo change their pattern of gene expression, which allows them to detach from their original location and migrate to another part of the embryo, where the pattern changes again to allow formation of a new organ.
Postdocs at this year’s top-ranked institutions get to tackle human health and disease from every angle. Scientists at the Donald Danforth Plant Science Center (#8 USA) search for ways to increase crop yield and enhance nutrition, while researchers a
The BeetleCam is back! And this time, it’s lion proof. The new, improved, and heavily armored version of the remote controlled, four-wheel camera buggy that met an untimely death in the jaws of a curious lioness in Tanzania in 2009 headed to the A
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