The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—from traumatic brain injury, to epilepsy, infection, or genetic predisposition—can activate brain immune cells—
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Isolating specific cell types from a mass of plant or animal tissue is laborious and tricky. To study epigenetic changes and genes that are expressed differently in different cell lineages—such as cancer cells versus normal cells, or the two types of
Using synchrotron rapid scanning X-ray fluorescence to map the distribution of trace metals in avian fossils over 120 million-year-old, researchers reconstruct the pigment patterns of their feathers—revealing some of the extinct birds' long-lost colo
The optogenetic toolset is composed of genetically encoded molecules that, when targeted to specific neurons in the brain, enable the electrical activity of those neurons to be driven or silenced by light. When these opsins are expressed in the lipid
Take a tour of the Linac Coherent Light Source (LCLS), whose ultra-powerful X-ray beam is being used to solve the structures of proteins that are notoriously hard to crystallize.
This animation illustrates optogenetics—a radical new technology for controlling brain activity with light. Ed Boyden, the co-inventor of this technology, is a professor at the MIT Media Lab and at the McGovern Institute for Brain Research, where he continues to develop new technologies for controlling brain activity.
A powerful new X-ray–generating laser is imaging smaller crystals than ever before.
When someone snorts or smokes cocaine, which is composed of small crystalline alkaloid molecules, the drug enters the bloodstream and from there eventually crosses into the heart, brain, and other organs. Cocaine quickens heart and respiratory rates,
Like other enveloped viruses, HIV exits its host cell enshrouded in the cell’s membrane, which contains membrane molecules such as the human leukocyte antigens (HLA). The HLA proteins act as a set of cell identification marks: every person expresses
Recent clinical trials have reignited the interest in simple anti-inflammatory drugs like aspirin for controlling the inflammation associated with cancer. The results suggest that these drugs reduced the risk of relapse as well as cancer formation ac
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