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image: OPSINS: Tools of the trade

OPSINS: Tools of the trade

By | July 1, 2011

The optogenetic toolset is composed of genetically encoded molecules that, when targeted to specific neurons in the brain, enable the electrical activity of those neurons to be driven or silenced by light. 


image: Meet the Crystal Smasher

Meet the Crystal Smasher

By | July 1, 2011

Take a tour of the Linac Coherent Light Source (LCLS), whose ultra-powerful X-ray beam is being used to solve the structures of proteins that are notoriously hard to crystallize.


image: Optogenetics: A Light Switch for Neurons

Optogenetics: A Light Switch for Neurons

By | July 1, 2011

This animation illustrates optogenetics—a radical new technology for controlling brain activity with light. 


image: Smashing Crystals

Smashing Crystals

July 1, 2011

A powerful new X-ray–generating laser is imaging smaller crystals than ever before.


image: The Anatomy of a High

The Anatomy of a High

By | June 3, 2011

When someone snorts or smokes cocaine, which is composed of small crystalline alkaloid molecules, the drug enters the bloodstream and from there eventually crosses into the heart, brain, and other organs. 


image: Part Human, Part HIV

Part Human, Part HIV

By | June 3, 2011

Like other enveloped viruses, HIV exits its host cell enshrouded in the cell’s membrane, which contains membrane molecules such as the human leukocyte antigens (HLA). 


image: Where Cancer and Inflammation Intersect

Where Cancer and Inflammation Intersect

By | April 1, 2011

Recent clinical trials have reignited the interest in simple anti-inflammatory drugs like aspirin for controlling the inflammation associated with cancer. 


image: Epigenetics—A Primer

Epigenetics—A Primer

By | March 1, 2011

Epigenetic events regulate the activities of genes without changing the DNA sequence. Different genes are expressed depending on the methyl-marks attached to DNA itself and by changes in the structure and/or composition of chromatin. 


image: The Worm Crew

The Worm Crew

By | February 1, 2011

Meet the people behind studies that use nematodes to treat inflammatory diseases. 


image: Intestinal Molecular Signaling

Intestinal Molecular Signaling

By | January 1, 2011

Microbes, both good and bad, can exert direct effects on host cells and vice versa. 


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