Shortly after a rat infested supply ship ran aground in Lord Howe Island off the east coast of Australia in 1918, the newly introduced mammals wiped out the island's phasmids—stick insects the size of a human hand. Ever since, phasmids have been cons
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Sangamo Biosciences is putting a different spin on gene therapy. Rather than replace or supplement a mutated gene with an accurate copy, Sangamo researchers are introducing a mutant copy of the gene for the HIV co-receptor CCR5 into the T cells of HI
It’s a well-known story: The peppered moth’s ancestral typica phenotype is white with dark speckles. In the decades following the Industrial Revolution, a new, soot-colored form, known as carbonaria, flourished and displaced the typica moths in the h
Telomeres are repetitive, noncoding sequences that cap the ends of linear chromosomes. They consist of hexameric nucleotide sequences (TTAGGG in humans) repeated hundreds to thousands of times. Telomeres protect the protein-coding sequences of DNA on
A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. In order to replicate the structure of an enzyme’s transition state, whic
Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. Through this mechanism, vitamin D promotes calcium absorption
Satellite imagery is giving biologists a whole new perspective on the phenomena they study.
Bucknell University mammalogist DeeAnn Reeder raises nets high into the darkened forest canopies of South Sudan to catch bats.
In late June 2009, a small group of mountain gorillas in Rwanda’s Volcanoes National Park began to fall ill. One by one, 11 of the dozen apes started exhibiting severe respiratory problems. An investigation led by wildlife veterinarian Jean-Felix Kin
In fewer than 15 years, nanomedicine has gone from fantasy to reality.
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