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image: Ubiquitin Chains in Action

Ubiquitin Chains in Action

By | July 1, 2012

Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role

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image: How Drugs Interact with a Baby’s Parts

How Drugs Interact with a Baby’s Parts

By | March 1, 2012

A lot changes in a child’s body over the course of development, and not all changes occur linearly: gene expression can fluctuate, and organs can perform different functions on the way to their final purpose in the body. Here are some of the key deve

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image: Inflammation, Pain, and Resolvins

Inflammation, Pain, and Resolvins

By | January 1, 2012

Not all inflammation leads to pain. Despite widespread infection followed by fever, colds rarely cause pain. But when some cytokines and certain immune cells are active near pain-sensing nerves, they trigger receptors that convey pain sensations to the brain.

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image: Bat Hunt

Bat Hunt

By | January 1, 2012

Bucknell University mammalogist DeeAnn Reeder raises nets high into the darkened forest canopies of South Sudan to catch bats.

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image: Teen DNA Detectives

Teen DNA Detectives

By | December 1, 2011

Genomicist Mark Stoeckle and three high school students have taken do-it-yourself science to a new level. 

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image: Designing Genetic Circuits

Designing Genetic Circuits

By | October 1, 2011

Near the turn of the millennium, James Collins and Stanislas Leibler independently undertook rather similar projects: design what would become synthetic biology’s seminal genetic circuits. And they came up with strikingly similar action plans.

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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

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image: New Blood for Gene Therapy

New Blood for Gene Therapy

By | June 13, 2011

Follow the success story of a young boy who, with the help of the Care for Rare Foundation, underwent stem cell therapy for Wiskott-Aldrich Syndrome.

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image: The Anatomy of a High

The Anatomy of a High

By | June 3, 2011

When someone snorts or smokes cocaine, which is composed of small crystalline alkaloid molecules, the drug enters the bloodstream and from there eventually crosses into the heart, brain, and other organs. 

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image: Part Human, Part HIV

Part Human, Part HIV

By | June 3, 2011

Like other enveloped viruses, HIV exits its host cell enshrouded in the cell’s membrane, which contains membrane molecules such as the human leukocyte antigens (HLA). 

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