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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 

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image: Suspected Effects of Vitamin D

Suspected Effects of Vitamin D

By | March 1, 2012

Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. 

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image: Teen DNA Detectives

Teen DNA Detectives

By | December 1, 2011

Genomicist Mark Stoeckle and three high school students have taken do-it-yourself science to a new level. 

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image: Designing Genetic Circuits

Designing Genetic Circuits

By | October 1, 2011

Near the turn of the millennium, James Collins and Stanislas Leibler independently undertook rather similar projects: design what would become synthetic biology’s seminal genetic circuits. And they came up with strikingly similar action plans.

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image: Swallowing the Surgeon

Swallowing the Surgeon

By | October 1, 2011

In fewer than 15 years, nanomedicine has gone from fantasy to reality.

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image: The Right Sort

The Right Sort

By | August 1, 2011

Isolating specific cell types from a mass of plant or animal tissue is laborious and tricky. 

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image: Best in Academia, 2011

Best in Academia, 2011

By | July 1, 2011

Meet some of the finalists of this year's Best Places to Work in Academia survey. 

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image: New Blood for Gene Therapy

New Blood for Gene Therapy

By | June 13, 2011

Follow the success story of a young boy who, with the help of the Care for Rare Foundation, underwent stem cell therapy for Wiskott-Aldrich Syndrome.

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image: The Anatomy of a High

The Anatomy of a High

By | June 3, 2011

When someone snorts or smokes cocaine, which is composed of small crystalline alkaloid molecules, the drug enters the bloodstream and from there eventually crosses into the heart, brain, and other organs. 

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image: Part Human, Part HIV

Part Human, Part HIV

By | June 3, 2011

Like other enveloped viruses, HIV exits its host cell enshrouded in the cell’s membrane, which contains membrane molecules such as the human leukocyte antigens (HLA). 

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