disease & medicine, neuroscience

Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.

Three studies show that tumor cells can behave like neurons.

Patients who suffer a traumatic brain injury may exhibit abnormally abundant tau protein many years later, a new in vivo imaging technique reveals.

Researchers link levels of a receptor in the brain to suicidal ideation in people with post-traumatic stress disorder.

Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.

The glia seem to make up part of a newly described sensory organ, the discoverers suggest.

The sei ion channel in fruit flies keeps their neuronal excitability in check.

A device implanted into mice can modulate brain circuit activity over long periods of time.

Carbon dioxide pumped into a bright chamber mimics a breathing host for the pest to target.

Boosting the levels of Akkermansia muciniphila in mouse guts slowed the progression of an ALS-like disease, while two other microbiome members were associated with more severe symptoms.

Some researchers and animal rights groups are amplifying their opposition to an assay that measures how long a rodent tries to stay afloat.

A 3-D printed prosthetic hand moves by reading the signals in forearm muscles.

The connectomes trace 385 neurons in the male worm and 302 neurons in the hermaphrodite worm.

The gut microbiome has been linked to depression, schizophrenia, and other neurological conditions, but it’s not yet clear whether the relationship is causal.

Johns Hopkins’s Ted Dawson discusses his lab’s demonstration that misfolded α-synuclein can move from the stomach to the brain and cause physical and cognitive symptoms.

Patients in a study of catheter ablation who showed signs of more injury to nerve cells and glia in the heart had fewer symptoms after the treatment.

An RNA analysis of human brain cells reveals gene expression changes in cortical neurons and microglia linked to autism spectrum disorder (ASD).

Researchers develop a system to deliver synthetic blood to isolated brains hours after death.

The drug promotes and sustains brain cell connectivity in mice, reversing the effects of chronic stress.