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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 

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image: Suspected Effects of Vitamin D

Suspected Effects of Vitamin D

By | March 1, 2012

Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. 

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image: 2011's Best and Brightest

2011's Best and Brightest

By | January 1, 2012

In its brief, 4-year history, The Scientist’s annual Top 10 Innovations contest has become a showcase of the coolest life science tools to emerge in the previous year. 

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image: Teen DNA Detectives

Teen DNA Detectives

By | December 1, 2011

Genomicist Mark Stoeckle and three high school students have taken do-it-yourself science to a new level. 

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image: Swallowing the Surgeon

Swallowing the Surgeon

By | October 1, 2011

In fewer than 15 years, nanomedicine has gone from fantasy to reality.

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image: The Right Sort

The Right Sort

By | August 1, 2011

Isolating specific cell types from a mass of plant or animal tissue is laborious and tricky. 

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image: Best in Academia, 2011

Best in Academia, 2011

By | July 1, 2011

Meet some of the finalists of this year's Best Places to Work in Academia survey. 

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image: Where Cancer and Inflammation Intersect

Where Cancer and Inflammation Intersect

By | April 1, 2011

Recent clinical trials have reignited the interest in simple anti-inflammatory drugs like aspirin for controlling the inflammation associated with cancer. 

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image: Death or Damage of Dopamine Neurons

Death or Damage of Dopamine Neurons

By | February 1, 2011

The hallmark pathology of Parkinson’s disease is the damage and death of dopamine producing neurons in the brain. 

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image: The Evolution of Volvox

The Evolution of Volvox

By | January 1, 2011

The volvocine algae are a model system for studying the evolution of multicellularity, as the group contains extant species ranging from the unicellular Chlamydomonas to a variety of colonial species and the full-fledged multicellular Volvox varieties.

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