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Michael Green in the lab, smiling at the camera
Molecular Biologist Michael Green Dies at 69
Beyond his achievements in academia, he also cofounded three pharmaceutical companies and filed 15 patents related to cancer therapeutics. 
Molecular Biologist Michael Green Dies at 69
Molecular Biologist Michael Green Dies at 69

Beyond his achievements in academia, he also cofounded three pharmaceutical companies and filed 15 patents related to cancer therapeutics. 

Beyond his achievements in academia, he also cofounded three pharmaceutical companies and filed 15 patents related to cancer therapeutics. 

genetics & genomics, genetics, cancer

Illustration of light blue speckled DNA helix on a dark background
Study Nearly Doubles Known Cancer-Linked Mutational Signatures
Jef Akst | Apr 22, 2022 | 2 min read
Analyzing the whole genome sequences of more than 18,000 tumors, researchers catalog nearly 60 new patterns of mutations that could inform cancer treatment.
Conceptual image showing fragmented X chromosomes
How Chaos in Chromosomes Helps Drive Cancer Spread
Samuel F. Bakhoum | Mar 1, 2022 | 10+ min read
A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.
Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022 | 2 min read
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
A tasmanian devil with its nose in the air
Deadly Facial Tumors Spur Tasmanian Devil Evolution: Study
Christie Wilcox, PhD | Jun 16, 2021 | 6 min read
The largest study to date of the animals’ genetics provides robust evidence that they are adapting to survive a highly lethal, contagious cancer scientists feared would cause their extinction.
clear blood draw tubes with peach-colored caps and white labels with a red banner that has a DNA double helix icon and the word text. inside the tubes is a conceptual drawing of a DNA double helix in white
FDA-Led Consortium Details Improvements Needed in Liquid Biopsies
Marcus A. Banks | May 19, 2021 | 4 min read
In the largest effort to date to standardize performance metrics of the cancer diagnostic across products, researchers say the products can likely detect advanced tumors reliably, but early-stage malignancies would remain a challenge.
No Transgenerational Effects of Chernobyl Radiation Found
Abby Olena, PhD | Apr 22, 2021 | 4 min read
The genomes of the children of people exposed to fallout from the Chernobyl nuclear accident appear to carry no trace of the incident.
Cancer May Be Driven by DNA Outside of Chromosomes
Paul Mischel | Apr 1, 2021 | 10+ min read
In the last decade, researchers have come to realize that tumors harbor bits of extrachromosomal DNA that can drive malignancy.
“Rogue” Protein Could Contribute to Humans’ High Cancer Rates
Asher Jones | Apr 1, 2021 | 2 min read
A mutant protein called Siglec-XII may promote carcinoma progression in humans, but inactivation of its gene seems to avoid the problem, according to a study.
Infographic: The Role of Extrachromosomal DNA in Cancer
Paul Mischel | Apr 1, 2021 | 2 min read
Researchers are uncovering how circular bits of DNA found in some cancer cells can help tumors evolve and kill.
primordial germ cells
Stray Germ Cells May Seed Female-Biased Cancerous Cysts
Ashley Yeager | Apr 1, 2019 | 2 min read
Similarities in gene expression hint at the origin of a certain type of pancreatic tumor that predominantly afflicts women.
Cancer-Specific Antigens Encoded in “Junk” DNA
Carolyn Wilke | Apr 1, 2019 | 2 min read
Researchers found that allegedly noncoding genetic material carries the instructions for many peptides that may help harness the immune system to fight cancer.
Researchers Publish First Pan-Cancer Genomic Analyses in Pediatric Patients
Catherine Offord | Feb 28, 2018 | 2 min read
Two large-scale studies reveal new insights into the genomic characteristics of childhood cancers.
Mutations Linked to Secondary Cancers
Jef Akst | Apr 4, 2017 | 2 min read
Childhood cancer survivors with mutations in certain cancer-risk genes have a higher risk of developing additional neoplasms later in life, according to research presented at the American Association for Cancer Research annual meeting.
Court Rules Gene Patents Valid
Cristina Luiggi | Aug 17, 2012 | 1 min read
Myriad Genetics can hold patents on the BRAC1 and BRAC2 oncogenes, but not on tests comparing DNA sequences.
Targeting DNA
Jef Akst | Jun 1, 2012 | 10+ min read
After 20 years of high-profile failure, gene therapy is finally well on its way to clinical approval.
Genome Digest
Cristina Luiggi | May 22, 2012 | 3 min read
What researchers are learning as they sequence, map, and decode species’ genomes
Genome Digest
Cristina Luiggi | Mar 7, 2012 | 3 min read
Meet the species whose DNA has recently been sequenced.
Top 7 in Genomics & Genetics
Bob Grant | Jul 19, 2011 | 3 min read
A snapshot of the most highly ranked articles in genomics, genetics, and related areas, from Faculty of 1000
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