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» genetics & genomics and disease/medicine

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image: The Cytokine Cycle

The Cytokine Cycle

By | September 1, 2011

The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.

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image: Battling Malaria in Africa

Battling Malaria in Africa

By | August 1, 2011

When general practitioner John Lusingu returned to his native Tanzania to do research on malaria, he was met with a total lack of science infrastructure. 

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image: Helpful Bacterial Metabolites

Helpful Bacterial Metabolites

By | August 1, 2011

While gut microbiota appear to have both positive and negative impacts on our  health, in the guts of healthy, lean individuals, the good outweighs the bad.  

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image: Harmful Bacterial Metabolites

Harmful Bacterial Metabolites

By | August 1, 2011

Gut bacteria that feed on healthy food appear to amplify the nutritional benefits of those foods. However, they also appear to amplify the undesirable effects of unhealthy food. 

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image: The Right Sort

The Right Sort

By | August 1, 2011

Isolating specific cell types from a mass of plant or animal tissue is laborious and tricky. 

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image: New Blood for Gene Therapy

New Blood for Gene Therapy

By | June 13, 2011

Follow the success story of a young boy who, with the help of the Care for Rare Foundation, underwent stem cell therapy for Wiskott-Aldrich Syndrome.

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image: Repairing hearts

Repairing hearts

By | June 9, 2011

Paul Riley of University College London discusses his new research, published June 8th in Nature.

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image: Medical Posters

Medical Posters

By | June 7, 2011

William Helfand began buying medically themed collectibles in the 1950s when he started working for Merck & Co. Over his 30-year career with the company, Helfand amassed thousands of posters and other old marketing paraphernalia.

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image: Part Human, Part HIV

Part Human, Part HIV

By | June 3, 2011

Like other enveloped viruses, HIV exits its host cell enshrouded in the cell’s membrane, which contains membrane molecules such as the human leukocyte antigens (HLA). 

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image: Death or Damage of Dopamine Neurons

Death or Damage of Dopamine Neurons

By | February 1, 2011

The hallmark pathology of Parkinson’s disease is the damage and death of dopamine producing neurons in the brain. 

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