genetics & genomics, epigenetics

From DNA damage to cellular miscommunication, aging is a mysterious and multifarious process.

A study finds a link between patterns of methylation in the human genome and people’s life span.

Documenting the epigenetic landscape of human innate immune cells reveals pathways essential for training macrophages.

Scientists show how roundworm daughter cells remember the histone modification patterns of their parents.

The stressors a female rat experiences during pregnancy can have repercussions for her granddaughters, a study shows. 

Epigenetic and genetic changes in the SKA2 gene are correlated with suicidal behaviors, researchers show.

Assessing mtDNA mutations among healthy people; heritability of intelligence; epigenetic inheritance of maternal malnutrition markers; consumers buy into DNA ancestry

Mice undernourished during pregnancy can transmit the effects of such nutritional stress to their sons’ germ cells, epigenetically.  

Molecular markers of a mother’s nutrition around the time of conception can be found in her child’s DNA.

Genome-wide effects of trisomy 21; RNA-based signs of transgenerational stress; depression and resilience; a call to overhaul US biomedical research system

A mistimed sleep cycle drastically reduces the number of genes that are expressed in a 24-hour rhythm.

DNA methylation status can predict age in various human tissues, a study shows.

Highlights from a series of three webinars on the future of genome research, held by The Scientist to celebrate 60 years of the DNA double helix

Making sense of the data deluge

Long non-protein-coding RNA (lncRNA) sequences are often transcribed from the opposite, or antisense, strand of a protein coding gene. In the past few years, research has shown that these lncRNAs play a number of regulatory roles in the cell. For exa

Epigenetic changes accrued over an organism’s lifetime may leave a permanent heritable mark on the genome, through the help of long noncoding RNAs.

Privacy advocates are arguing that collecting genetic data upon arrest is an invasion of privacy, given recent evidence that 80 percent of the human genome is functional.

Random chance, plus small differences in uterine environments, give rise to divergent epigenetic patterns in identical twins.

Exposure to an environmental toxin can affect future generations’ ability to handle stressful conditions.

Scientists are beginning to discover myriad strategies tumors use to avoid attacks by anti-cancer drugs.