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image: Grass Routes

Grass Routes

By | July 17, 2017

Researchers are discovering a suite of new locations and functions of endocannabinoid receptors that play roles in sickness and in health.

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image: Uncovering Functions of Circular RNAs

Uncovering Functions of Circular RNAs

By | July 17, 2017

Recent research has revealed many surprises about circular RNAs, from findings that they are translated in vivo to links between their expression and disease.

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image: How Cancers Evolve Drug Resistance

How Cancers Evolve Drug Resistance

By | April 1, 2017

Researchers unravel the sophisticated ways cancers evade treatments, including immunotherapies, designed to destroy them.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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image: RNA Interference Between Kingdoms

RNA Interference Between Kingdoms

By | February 1, 2017

Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of pesticides.

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image: May the Force Be with You

May the Force Be with You

By | February 1, 2017

The dissection of how cells sense and propagate physical forces is leading to exciting new tools and discoveries in mechanobiology and mechanomedicine.

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image: Repurposing Existing Drugs for New Indications

Repurposing Existing Drugs for New Indications

By | January 1, 2017

An entire industry has sprung up around resurrecting failed drugs and recycling existing compounds for novel indications.

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image: Nuclear Pores Come into Sharper Focus

Nuclear Pores Come into Sharper Focus

By and | December 1, 2016

Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.

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image: Top 10 Innovations 2016

Top 10 Innovations 2016

By | December 1, 2016

This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.

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