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tag drug development neuroscience genetics genomics clinical trials infectious disease

Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
An artistic rendering of blue neurons against a white background
Participant’s Diagnosis Halts Gene Therapy Clinical Trial
Amanda Heidt | Aug 12, 2021 | 3 min read
The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.
3D illustration of greenish-brown rod-shaped bacteria.
A Novel Molecule to Tackle Drug-Resistant Bugs
Aparna Nathan, PhD | Feb 12, 2024 | 4 min read
A new antibiotic is the first to block a critical transport mechanism in drug-resistant bacteria.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
The Breakthrough Prize ?Trophy
2024 Breakthrough Prizes in Life Sciences
Danielle Gerhard, PhD | Sep 14, 2023 | 10 min read
This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.
Stalking Infectious Disease
Eugene Russo | Jun 11, 2000 | 8 min read
Graphic: Cathleen Heard Law enforcement officials routinely use DNA fingerprinting as a tool to get the guilty punished. Defense lawyers often rely on the same tool to free the innocent. Though their labs may be less dramatic settings than criminal courtrooms, life science researchers also use DNA fingerprinting, but rather than capturing criminals, their goal is to keep tabs on a different sort of culprit: infectious disease. The technology has revolutionized the way diseases are tracked and th
Introduction to AAV Gene Therapies
Introduction to AAV Gene Therapies
Nicole Stivers, PhD | Jun 29, 2023 | 4 min read
Small-scale successes in rare disease treatments prime large-scale industry innovations.

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