neuroscience, drug development, cell & molecular biology

The race to develop analgesic drugs that inhibit sodium channel Na_V1.7 is revealing a complex sensory role for the protein.

Since the mid-2000s, the voltage-gated sodium channel Na_V1.7 has emerged as a promising target for a new class of analgesics.

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.

The researcher who helped develop an Alzheimer's treatment now in clinical trials warns that the compound may actually impair memory.