Understanding oncogenesis at the molecular level offers the prospect of tailoring treatments much more precisely for patients with advanced cases of this deadliest of skin cancers.
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Can tumors—which can originate from, and often resemble, chronically inflamed tissue—be curtailed using familiar anti-inflammatory agents, without their side effects?
The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies.
There are many ways that epigenetic effects regulate the activation or repression of genes. Here are a few molecular tricks cells use to read off the right genetic program.
Research in behavioral epigenetics is seeking evidence that links experience to biochemistry to gene expression and back out again.
A father’s determination to help his son resulted in an experimental treatment for autism that uses roundworms to modulate inflammatory immune responses. Can the worms be used to treat other diseases?
Amygdala responses to the facial signals of others predict both normal and abnormal emotional states. An understanding of the brain chemistry underlying these responses will lead to new strategies for treating and predicting psychopathology.
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.
As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.
Indirect effects of global climate change threaten the health of hundreds of millions of people. The very uncertainty that shrouds this issue must serve as an organizing principle for adaptation to its ill effects.
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